An intermolecular salt bridge linking substrate binding and P1 substrate specificity switch of arterivirus 3C-like proteases

Equine arteritis virus (EAV) and porcine reproductive and respiratory syndrome virus (PRRSV) represent two members of the family Arteriviridae and pose a major threat to the equine- and swine-breeding industries throughout the world. Previously, we and others demonstrated that PRRSV 3C-like protease...

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Detalles Bibliográficos
Autores principales: Chen, Qian, Zhou, Junwei, Yang, Zhixiang, Guo, Jiahui, Liu, Zimin, Sun, Xinyi, Jiang, Qingshi, Fang, Liurong, Wang, Dang, Xiao, Shaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271976/
https://www.ncbi.nlm.nih.gov/pubmed/35832618
http://dx.doi.org/10.1016/j.csbj.2022.06.059

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