Cargando…

Predicting 3D chromatin interactions from DNA sequence using Deep Learning

Gene regulation in eukaryotes is profoundly shaped by the 3D organization of chromatin within the cell nucleus. Distal regulatory interactions between enhancers and their target genes are widespread and many causal loci underlying heritable agricultural or clinical traits have been mapped to distal...

Descripción completa

Detalles Bibliográficos
Autores principales: Piecyk, Robert S., Schlegel, Luca, Johannes, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271978/
https://www.ncbi.nlm.nih.gov/pubmed/35832620
http://dx.doi.org/10.1016/j.csbj.2022.06.047