T cells isolated from G-CSF-treated multiple myeloma patients are suitable for the generation of BCMA-directed CAR-T cells

Autologous cell immunotherapy using B cell maturation antigen (BCMA)-targeted chimeric antigen receptor (CAR)-T cells is an effective novel treatment for multiple myeloma (MM). This therapy has only been used for relapsed and refractory patients, at which stage the endogenous T cells used to produce...

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Detalles Bibliográficos
Autores principales: Battram, Anthony M., Oliver-Caldés, Aina, Suárez-Lledó, Maria, Lozano, Miquel, Bosch i Crespo, Miquel, Martínez-Cibrián, Núria, Cid, Joan, Moreno, David F., Rodríguez-Lobato, Luis Gerardo, Urbano-Ispizua, Alvaro, Fernández de Larrea, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271987/
https://www.ncbi.nlm.nih.gov/pubmed/35859694
http://dx.doi.org/10.1016/j.omtm.2022.06.010

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