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Oxytocin administration versus emotion training in healthy males: considerations for future research

Identifying emotions correctly is essential for successful social interaction. There is therefore a keen interest in designing therapeutic interventions to improve emotion recognition in individuals who struggle with social interaction. The neuropeptide oxytocin has been proposed as a potential phys...

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Autores principales: Daughters, Katie, Rees, D. Aled, Hunnikin, Laura, Wells, Amy, Hall, Jeremy, van Goozen, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272145/
https://www.ncbi.nlm.nih.gov/pubmed/35858104
http://dx.doi.org/10.1098/rstb.2021.0056
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author Daughters, Katie
Rees, D. Aled
Hunnikin, Laura
Wells, Amy
Hall, Jeremy
van Goozen, Stephanie
author_facet Daughters, Katie
Rees, D. Aled
Hunnikin, Laura
Wells, Amy
Hall, Jeremy
van Goozen, Stephanie
author_sort Daughters, Katie
collection PubMed
description Identifying emotions correctly is essential for successful social interaction. There is therefore a keen interest in designing therapeutic interventions to improve emotion recognition in individuals who struggle with social interaction. The neuropeptide oxytocin has been proposed as a potential physiological intervention due to its important role in emotion recognition and other aspects of social cognition. However, there are a number of caveats to consider with the current form of intranasal oxytocin commonly used in the literature. Psychological interventions, on the other hand, do not carry the same caveats, and there is, therefore, a need to understand how intranasal oxytocin administration compares to psychological interventions designed to target the same psychological phenomena; and whether a combined intervention approach may provide additive benefits. Here we present a pilot, proof-of-concept study in healthy volunteers comparing the effect of intranasal oxytocin against a validated emotion training programme, finding that the psychological intervention, and not intranasal oxytocin, improved emotion recognition specifically for angry expressions. We discuss the theoretical implications of the research for future clinical trials. This article is part of the theme issue ‘Interplays between oxytocin and other neuromodulators in shaping complex social behaviours’.
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spelling pubmed-92721452022-11-22 Oxytocin administration versus emotion training in healthy males: considerations for future research Daughters, Katie Rees, D. Aled Hunnikin, Laura Wells, Amy Hall, Jeremy van Goozen, Stephanie Philos Trans R Soc Lond B Biol Sci Articles Identifying emotions correctly is essential for successful social interaction. There is therefore a keen interest in designing therapeutic interventions to improve emotion recognition in individuals who struggle with social interaction. The neuropeptide oxytocin has been proposed as a potential physiological intervention due to its important role in emotion recognition and other aspects of social cognition. However, there are a number of caveats to consider with the current form of intranasal oxytocin commonly used in the literature. Psychological interventions, on the other hand, do not carry the same caveats, and there is, therefore, a need to understand how intranasal oxytocin administration compares to psychological interventions designed to target the same psychological phenomena; and whether a combined intervention approach may provide additive benefits. Here we present a pilot, proof-of-concept study in healthy volunteers comparing the effect of intranasal oxytocin against a validated emotion training programme, finding that the psychological intervention, and not intranasal oxytocin, improved emotion recognition specifically for angry expressions. We discuss the theoretical implications of the research for future clinical trials. This article is part of the theme issue ‘Interplays between oxytocin and other neuromodulators in shaping complex social behaviours’. The Royal Society 2022-08-29 2022-07-11 /pmc/articles/PMC9272145/ /pubmed/35858104 http://dx.doi.org/10.1098/rstb.2021.0056 Text en © 2022 The Authors. https://creativecommons.org/licenses/by/4.0/Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, provided the original author and source are credited.
spellingShingle Articles
Daughters, Katie
Rees, D. Aled
Hunnikin, Laura
Wells, Amy
Hall, Jeremy
van Goozen, Stephanie
Oxytocin administration versus emotion training in healthy males: considerations for future research
title Oxytocin administration versus emotion training in healthy males: considerations for future research
title_full Oxytocin administration versus emotion training in healthy males: considerations for future research
title_fullStr Oxytocin administration versus emotion training in healthy males: considerations for future research
title_full_unstemmed Oxytocin administration versus emotion training in healthy males: considerations for future research
title_short Oxytocin administration versus emotion training in healthy males: considerations for future research
title_sort oxytocin administration versus emotion training in healthy males: considerations for future research
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272145/
https://www.ncbi.nlm.nih.gov/pubmed/35858104
http://dx.doi.org/10.1098/rstb.2021.0056
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