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Necrotizing pneumonia requiring prolonged extracorporeal membrane oxygenation: Pushing the boundaries in pediatric ECMO

Extracorporeal membrane oxygenation (ECMO) is a life‐saving rescue therapy used in acute respiratory failure refractory to invasive mechanical ventilation. Recent studies on positive outcomes of extended ECMO therapy are promising. We describe a case of a 2‐year 8‐month‐old female child with necroti...

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Autores principales: R. R., Pravin, Chandran, Suresh, Tan, Yi Hua, Thomas, Biju, Lee, Jan Hau, Menon, Anuradha P., Ong, Kim Kiat, Kumar Pugalenthi, Arun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272214/
https://www.ncbi.nlm.nih.gov/pubmed/35846934
http://dx.doi.org/10.1002/ccr3.5973
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author R. R., Pravin
Chandran, Suresh
Tan, Yi Hua
Thomas, Biju
Lee, Jan Hau
Menon, Anuradha P.
Ong, Kim Kiat
Kumar Pugalenthi, Arun
author_facet R. R., Pravin
Chandran, Suresh
Tan, Yi Hua
Thomas, Biju
Lee, Jan Hau
Menon, Anuradha P.
Ong, Kim Kiat
Kumar Pugalenthi, Arun
author_sort R. R., Pravin
collection PubMed
description Extracorporeal membrane oxygenation (ECMO) is a life‐saving rescue therapy used in acute respiratory failure refractory to invasive mechanical ventilation. Recent studies on positive outcomes of extended ECMO therapy are promising. We describe a case of a 2‐year 8‐month‐old female child with necrotizing pneumonia secondary to Streptococcus pneumoniae, Influenza A, and Mycoplasma pneumoniae, who survived with intact neurological function and no long‐term adverse outcomes after a prolonged ECMO run of 86 days. To the best of our knowledge, this is one of the longer durations of ECMO with transplant‐free survival in a pediatric patient requiring respiratory support with good recovery and a good functional outcome. Allowing time for native lung recovery is pivotal for optimal recovery, despite significant lung injury due to the underlying disease process. With evolving ECMO experience, clinicians may need to re‐consider the conventional maximum duration of ECMO in children with severe respiratory failure on a case‐by‐case basis.
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spelling pubmed-92722142022-07-15 Necrotizing pneumonia requiring prolonged extracorporeal membrane oxygenation: Pushing the boundaries in pediatric ECMO R. R., Pravin Chandran, Suresh Tan, Yi Hua Thomas, Biju Lee, Jan Hau Menon, Anuradha P. Ong, Kim Kiat Kumar Pugalenthi, Arun Clin Case Rep Case Report Extracorporeal membrane oxygenation (ECMO) is a life‐saving rescue therapy used in acute respiratory failure refractory to invasive mechanical ventilation. Recent studies on positive outcomes of extended ECMO therapy are promising. We describe a case of a 2‐year 8‐month‐old female child with necrotizing pneumonia secondary to Streptococcus pneumoniae, Influenza A, and Mycoplasma pneumoniae, who survived with intact neurological function and no long‐term adverse outcomes after a prolonged ECMO run of 86 days. To the best of our knowledge, this is one of the longer durations of ECMO with transplant‐free survival in a pediatric patient requiring respiratory support with good recovery and a good functional outcome. Allowing time for native lung recovery is pivotal for optimal recovery, despite significant lung injury due to the underlying disease process. With evolving ECMO experience, clinicians may need to re‐consider the conventional maximum duration of ECMO in children with severe respiratory failure on a case‐by‐case basis. John Wiley and Sons Inc. 2022-07-11 /pmc/articles/PMC9272214/ /pubmed/35846934 http://dx.doi.org/10.1002/ccr3.5973 Text en © 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
R. R., Pravin
Chandran, Suresh
Tan, Yi Hua
Thomas, Biju
Lee, Jan Hau
Menon, Anuradha P.
Ong, Kim Kiat
Kumar Pugalenthi, Arun
Necrotizing pneumonia requiring prolonged extracorporeal membrane oxygenation: Pushing the boundaries in pediatric ECMO
title Necrotizing pneumonia requiring prolonged extracorporeal membrane oxygenation: Pushing the boundaries in pediatric ECMO
title_full Necrotizing pneumonia requiring prolonged extracorporeal membrane oxygenation: Pushing the boundaries in pediatric ECMO
title_fullStr Necrotizing pneumonia requiring prolonged extracorporeal membrane oxygenation: Pushing the boundaries in pediatric ECMO
title_full_unstemmed Necrotizing pneumonia requiring prolonged extracorporeal membrane oxygenation: Pushing the boundaries in pediatric ECMO
title_short Necrotizing pneumonia requiring prolonged extracorporeal membrane oxygenation: Pushing the boundaries in pediatric ECMO
title_sort necrotizing pneumonia requiring prolonged extracorporeal membrane oxygenation: pushing the boundaries in pediatric ecmo
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272214/
https://www.ncbi.nlm.nih.gov/pubmed/35846934
http://dx.doi.org/10.1002/ccr3.5973
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