A Novel BRD Family PROTAC Inhibitor dBET1 Exerts Great Anti-Cancer Effects by Targeting c-MYC in Acute Myeloid Leukemia Cells

Acute myeloid leukemia (AML) represents an aggressive hematopoietic malignancy with a prognosis inferior to that of other leukemias. Recent targeted therapies offer new opportunities to achieve better treatment outcomes. However, due to the complex heterogeneity of AML, its prognosis remains dismal....

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Detalles Bibliográficos
Autores principales: Zhang, Kunlong, Gao, Li, Wang, Jianwei, Chu, Xinran, Zhang, Zimu, Zhang, Yongping, Fang, Fang, Tao, Yanfang, Li, Xiaolu, Tian, Yuanyuan, Li, Zhiheng, Sang, Xu, Ma, Li, Lu, Lihui, Chen, Yanling, Yu, Juanjuan, Zhuo, Ran, Wu, Shuiyan, Pan, Jian, Hu, Shaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pathology and Oncology Archive
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272305/
https://www.ncbi.nlm.nih.gov/pubmed/35832114
http://dx.doi.org/10.3389/pore.2022.1610447

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