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Effects of general and central adiposity on circulating lipoprotein, lipid, and metabolite levels in UK Biobank: A multivariable Mendelian randomization study

BACKGROUND: The direct effects of general adiposity (body mass index (BMI)) and central adiposity (waist-to-hip-ratio (WHR)) on circulating lipoproteins, lipids, and metabolites are unknown. METHODS: We used new metabolic data from UK Biobank (N=109,532, a five-fold higher N over previous studies)....

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Detalles Bibliográficos
Autores principales:	Bell, Joshua A., Richardson, Tom G., Wang, Qin, Sanderson, Eleanor, Palmer, Tom, Walker, Venexia, O'Keeffe, Linda M., Timpson, Nicholas J., Cichonska, Anna, Julkunen, Heli, Würtz, Peter, Holmes, Michael V., Davey Smith, George
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272390/ https://www.ncbi.nlm.nih.gov/pubmed/35832062 http://dx.doi.org/10.1016/j.lanepe.2022.100457

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