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Selectivity profile comparison for certain γ-butyrolactone and oxazolidinone-based ligands on a sigma 2 receptor over sigma 1: a molecular docking approach

Sigma receptors (σ(1) R and σ(2) R) are pharmacologically characterized membrane-bound receptors that bind a wide range of chemical compounds. Alzheimer's disease, traumatic brain injury, schizophrenia, and neuropathic pain have all been associated with abnormal σ(2) activity. The σ(2) receptor...

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Detalles Bibliográficos
Autores principales:	Bhandare, Richie R., Sigalapalli, Dilep Kumar, Shaik, Afzal B., Canney, Daniel J., Blass, Benjamin E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2022
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272471/ https://www.ncbi.nlm.nih.gov/pubmed/35919619 http://dx.doi.org/10.1039/d2ra03497b

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