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Heterogeneous Distribution of Genetic Mutations in Myosin Binding Protein-C Paralogs

Myosin binding protein-C (MyBP-C) is a sarcomeric protein which regulates the force of contraction in striated muscles. Mutations in the MYBPC family of genes, including slow skeletal (MYBPC1), fast skeletal (MYBPC2) and cardiac (MYBPC3), can result in cardiac and skeletal myopathies. Nonetheless, t...

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Detalles Bibliográficos
Autores principales:	Desai, Darshini A., Rao, Vinay J., Jegga, Anil G., Dhandapany, Perundurai S., Sadayappan, Sakthivel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272480/ https://www.ncbi.nlm.nih.gov/pubmed/35832193 http://dx.doi.org/10.3389/fgene.2022.896117

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