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Descriptive Epidemiology of Gastrointestinal Cancers: Results from National Cancer Registry Programme, India

PURPOSE: This study aims to determine the incidence, histology, clinical extent of disease, and trends of gastrointestinal (GI) cancers in India. METHODS: GI cancer cases diagnosed between 2012-2016 from 28 Population-Based Cancer Registries and 58 Hospital Based Cancer Registries under the National...

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Autores principales: S, Shakuntala T, Krishnan, Sathishkumar Kumar, Das, Priyanka, Sudarshan, Kondalli Lakshminarayana, Kotian, Chitra M, Santhappan, Stephen, Vishwakarma, Monesh Baburao, N, Sureshkumar, Mathur, Prashant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272639/
https://www.ncbi.nlm.nih.gov/pubmed/35225451
http://dx.doi.org/10.31557/APJCP.2022.23.2.409
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author S, Shakuntala T
Krishnan, Sathishkumar Kumar
Das, Priyanka
Sudarshan, Kondalli Lakshminarayana
Kotian, Chitra M
Santhappan, Stephen
Vishwakarma, Monesh Baburao
N, Sureshkumar
Mathur, Prashant
author_facet S, Shakuntala T
Krishnan, Sathishkumar Kumar
Das, Priyanka
Sudarshan, Kondalli Lakshminarayana
Kotian, Chitra M
Santhappan, Stephen
Vishwakarma, Monesh Baburao
N, Sureshkumar
Mathur, Prashant
author_sort S, Shakuntala T
collection PubMed
description PURPOSE: This study aims to determine the incidence, histology, clinical extent of disease, and trends of gastrointestinal (GI) cancers in India. METHODS: GI cancer cases diagnosed between 2012-2016 from 28 Population-Based Cancer Registries and 58 Hospital Based Cancer Registries under the National Cancer Registry Programme were included. Crude incidence rate and age-standardized incidence rates (AARs) were calculated. Joinpoint regression program, 4.0.1 was used for trend analysis for data from 1982 to 2016, and a P-value of <<0.05 was considered statistically significant. RESULTS: GI cancers’ occurrence was more common among men (60.5%) than in women (39.5%). The incidence of GI cancer was highest in India’s northeast region, Aizawl district (AAR 126.9) among males, and in Papumpare district (AAR 75.9) among females. The commonest cancer among men was cancer of the esophagus (28.2%), followed by stomach cancer (21%) and rectum cancer (14.3%). Among women, cancer of the esophagus (25.7%), gallbladder (23.8%), stomach (14.8%), and rectum (14.6%) were common. Adenocarcinoma (57.83%) was the commonest type of GI tumors, followed by Squamous Cell neoplasms (25.99%). Majority of the GI cancers presented at the locoregional stage, but cancer of the gall bladder and pancreas presented at advanced stages. A rising trend for cancers of the colon, rectum, liver, gall bladder, pancreas was seen, while a declining trend was observed for stomach and oesophageal cancer. CONCLUSION: Our study highlights an increasing magnitude of GI cancers across different regions of India. Cancer registries form an essential tool for surveillance of GI cancers thus guiding prevention, early detection, and control programs.
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spelling pubmed-92726392022-07-14 Descriptive Epidemiology of Gastrointestinal Cancers: Results from National Cancer Registry Programme, India S, Shakuntala T Krishnan, Sathishkumar Kumar Das, Priyanka Sudarshan, Kondalli Lakshminarayana Kotian, Chitra M Santhappan, Stephen Vishwakarma, Monesh Baburao N, Sureshkumar Mathur, Prashant Asian Pac J Cancer Prev Research Article PURPOSE: This study aims to determine the incidence, histology, clinical extent of disease, and trends of gastrointestinal (GI) cancers in India. METHODS: GI cancer cases diagnosed between 2012-2016 from 28 Population-Based Cancer Registries and 58 Hospital Based Cancer Registries under the National Cancer Registry Programme were included. Crude incidence rate and age-standardized incidence rates (AARs) were calculated. Joinpoint regression program, 4.0.1 was used for trend analysis for data from 1982 to 2016, and a P-value of <<0.05 was considered statistically significant. RESULTS: GI cancers’ occurrence was more common among men (60.5%) than in women (39.5%). The incidence of GI cancer was highest in India’s northeast region, Aizawl district (AAR 126.9) among males, and in Papumpare district (AAR 75.9) among females. The commonest cancer among men was cancer of the esophagus (28.2%), followed by stomach cancer (21%) and rectum cancer (14.3%). Among women, cancer of the esophagus (25.7%), gallbladder (23.8%), stomach (14.8%), and rectum (14.6%) were common. Adenocarcinoma (57.83%) was the commonest type of GI tumors, followed by Squamous Cell neoplasms (25.99%). Majority of the GI cancers presented at the locoregional stage, but cancer of the gall bladder and pancreas presented at advanced stages. A rising trend for cancers of the colon, rectum, liver, gall bladder, pancreas was seen, while a declining trend was observed for stomach and oesophageal cancer. CONCLUSION: Our study highlights an increasing magnitude of GI cancers across different regions of India. Cancer registries form an essential tool for surveillance of GI cancers thus guiding prevention, early detection, and control programs. West Asia Organization for Cancer Prevention 2022-02 /pmc/articles/PMC9272639/ /pubmed/35225451 http://dx.doi.org/10.31557/APJCP.2022.23.2.409 Text en https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-Non Commercial 4.0 International License. https://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Research Article
S, Shakuntala T
Krishnan, Sathishkumar Kumar
Das, Priyanka
Sudarshan, Kondalli Lakshminarayana
Kotian, Chitra M
Santhappan, Stephen
Vishwakarma, Monesh Baburao
N, Sureshkumar
Mathur, Prashant
Descriptive Epidemiology of Gastrointestinal Cancers: Results from National Cancer Registry Programme, India
title Descriptive Epidemiology of Gastrointestinal Cancers: Results from National Cancer Registry Programme, India
title_full Descriptive Epidemiology of Gastrointestinal Cancers: Results from National Cancer Registry Programme, India
title_fullStr Descriptive Epidemiology of Gastrointestinal Cancers: Results from National Cancer Registry Programme, India
title_full_unstemmed Descriptive Epidemiology of Gastrointestinal Cancers: Results from National Cancer Registry Programme, India
title_short Descriptive Epidemiology of Gastrointestinal Cancers: Results from National Cancer Registry Programme, India
title_sort descriptive epidemiology of gastrointestinal cancers: results from national cancer registry programme, india
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272639/
https://www.ncbi.nlm.nih.gov/pubmed/35225451
http://dx.doi.org/10.31557/APJCP.2022.23.2.409
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