Beth Levine’s Legacy: From the Discovery of BECN1 to Therapies. A Mentees’ Perspective

With great sadness, the scientific community received the news of the loss of Beth Levine on 15 June 2020. Dr. Levine was a pioneer in the autophagy field and work in her lab led not only to a better understanding of the molecular mechanisms regulating the pathway, but also its implications in multi...

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Autores principales: An, Zhenyi, Chiang, Wei-Chung, Fernández, Álvaro F., Franco, Luis H., He, CongCong, Huang, Shu-Yi, Lee, Eunmyong, Liu, Yang, Sebti, Salwa, Shoji-Kawata, Sanae, Sirasanagandla, Shyam, Wang, Richard C., Wei, Yongjie, Zhao, Yuting, Vega-Rubin-de-Celis, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273008/
https://www.ncbi.nlm.nih.gov/pubmed/35832792
http://dx.doi.org/10.3389/fcell.2022.891332
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author An, Zhenyi
Chiang, Wei-Chung
Fernández, Álvaro F.
Franco, Luis H.
He, CongCong
Huang, Shu-Yi
Lee, Eunmyong
Liu, Yang
Sebti, Salwa
Shoji-Kawata, Sanae
Sirasanagandla, Shyam
Wang, Richard C.
Wei, Yongjie
Zhao, Yuting
Vega-Rubin-de-Celis, Silvia
author_facet An, Zhenyi
Chiang, Wei-Chung
Fernández, Álvaro F.
Franco, Luis H.
He, CongCong
Huang, Shu-Yi
Lee, Eunmyong
Liu, Yang
Sebti, Salwa
Shoji-Kawata, Sanae
Sirasanagandla, Shyam
Wang, Richard C.
Wei, Yongjie
Zhao, Yuting
Vega-Rubin-de-Celis, Silvia
author_sort An, Zhenyi
collection PubMed
description With great sadness, the scientific community received the news of the loss of Beth Levine on 15 June 2020. Dr. Levine was a pioneer in the autophagy field and work in her lab led not only to a better understanding of the molecular mechanisms regulating the pathway, but also its implications in multiple physiological and pathological conditions, including its role in development, host defense, tumorigenesis, aging or metabolism. This review does not aim to provide a comprehensive view of autophagy, but rather an outline of some of the discoveries made by the group of Beth Levine, from the perspective of some of her own mentees, hoping to honor her legacy in science.
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spelling pubmed-92730082022-07-12 Beth Levine’s Legacy: From the Discovery of BECN1 to Therapies. A Mentees’ Perspective An, Zhenyi Chiang, Wei-Chung Fernández, Álvaro F. Franco, Luis H. He, CongCong Huang, Shu-Yi Lee, Eunmyong Liu, Yang Sebti, Salwa Shoji-Kawata, Sanae Sirasanagandla, Shyam Wang, Richard C. Wei, Yongjie Zhao, Yuting Vega-Rubin-de-Celis, Silvia Front Cell Dev Biol Cell and Developmental Biology With great sadness, the scientific community received the news of the loss of Beth Levine on 15 June 2020. Dr. Levine was a pioneer in the autophagy field and work in her lab led not only to a better understanding of the molecular mechanisms regulating the pathway, but also its implications in multiple physiological and pathological conditions, including its role in development, host defense, tumorigenesis, aging or metabolism. This review does not aim to provide a comprehensive view of autophagy, but rather an outline of some of the discoveries made by the group of Beth Levine, from the perspective of some of her own mentees, hoping to honor her legacy in science. Frontiers Media S.A. 2022-06-27 /pmc/articles/PMC9273008/ /pubmed/35832792 http://dx.doi.org/10.3389/fcell.2022.891332 Text en Copyright © 2022 An, Chiang, Fernández, Franco, He, Huang, Lee, Liu, Sebti, Shoji-Kawata, Sirasanagandla, Wang, Wei, Zhao and Vega-Rubin-de-Celis. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cell and Developmental Biology
An, Zhenyi
Chiang, Wei-Chung
Fernández, Álvaro F.
Franco, Luis H.
He, CongCong
Huang, Shu-Yi
Lee, Eunmyong
Liu, Yang
Sebti, Salwa
Shoji-Kawata, Sanae
Sirasanagandla, Shyam
Wang, Richard C.
Wei, Yongjie
Zhao, Yuting
Vega-Rubin-de-Celis, Silvia
Beth Levine’s Legacy: From the Discovery of BECN1 to Therapies. A Mentees’ Perspective
title Beth Levine’s Legacy: From the Discovery of BECN1 to Therapies. A Mentees’ Perspective
title_full Beth Levine’s Legacy: From the Discovery of BECN1 to Therapies. A Mentees’ Perspective
title_fullStr Beth Levine’s Legacy: From the Discovery of BECN1 to Therapies. A Mentees’ Perspective
title_full_unstemmed Beth Levine’s Legacy: From the Discovery of BECN1 to Therapies. A Mentees’ Perspective
title_short Beth Levine’s Legacy: From the Discovery of BECN1 to Therapies. A Mentees’ Perspective
title_sort beth levine’s legacy: from the discovery of becn1 to therapies. a mentees’ perspective
topic Cell and Developmental Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273008/
https://www.ncbi.nlm.nih.gov/pubmed/35832792
http://dx.doi.org/10.3389/fcell.2022.891332
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