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Development and Use of a Monoclonal Antibody Specific for the Candida albicans Cell-Surface Protein Hwp1

The Candida albicans cell-surface protein Hwp1 functions in adhesion to the host and in biofilm formation. A peptide from the Gln-Pro-rich adhesive domain of Hwp1 was used to raise monoclonal antibody (MAb) 2-E8. MAb 2-E8 specificity for Hwp1 was demonstrated using a hwp1/hwp1 C. albicans isolate an...

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Detalles Bibliográficos
Autores principales: Oh, Soon-Hwan, Martin-Yken, Hélène, Coleman, David A., Dague, Etienne, Hoyer, Lois L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273023/
https://www.ncbi.nlm.nih.gov/pubmed/35832385
http://dx.doi.org/10.3389/fcimb.2022.907453