Cargando…

Host chitinase 3-like-1 is a universal therapeutic target for SARS-CoV-2 viral variants in COVID-19

Coronavirus disease 2019 (COVID-19) is the disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2; SC2), which has caused a worldwide pandemic with striking morbidity and mortality. Evaluation of SC2 strains demonstrated impressive genetic variability, and many of these viral...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kamle, Suchitra, Ma, Bing, Lee, Chang Min, Schor, Gail, Zhou, Yang, Lee, Chun Geun, Elias, Jack A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Microbiology and Infectious Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273216/ https://www.ncbi.nlm.nih.gov/pubmed/35735790 http://dx.doi.org/10.7554/eLife.78273

Ejemplares similares

Targeting Chitinase 1 and Chitinase 3-Like 1 as Novel Therapeutic Strategy of Pulmonary Fibrosis
por: Lee, Suh-Young, et al.
Publicado: (2022)

Chitinase 3-like-1 is a therapeutic target that mediates the effects of aging in COVID-19
por: Kamle, Suchitra, et al.
Publicado: (2021)

Role of Chitinase 3-Like 1 Protein in the Pathogenesis of Hepatic Insulin Resistance in Nonalcoholic Fatty Liver Disease
por: Zhang, Songhua, et al.
Publicado: (2021)

Pressure-driven release of viral genome into a host nucleus is a mechanism leading to herpes infection
por: Brandariz-Nuñez, Alberto, et al.
Publicado: (2019)

Temporal proteomic analysis of HIV infection reveals remodelling of the host phosphoproteome by lentiviral Vif variants
por: Greenwood, Edward JD, et al.
Publicado: (2016)

Vaccination reduces viral load and accelerates viral clearance in SARS-CoV-2 Delta variant-infected patients
por: Li, Hongxia, et al.
Publicado: (2023)

Viral-inducible Argonaute18 confers broad-spectrum virus resistance in rice by sequestering a host microRNA
por: Wu, Jianguo, et al.
Publicado: (2015)

Estimating Vaccine Efficacy Against Transmission via Effect on Viral Load
por: Kennedy-Shaffer, Lee, et al.
Publicado: (2021)

Really exasperating viral protein from HIV
por: Williamson, James R
Publicado: (2015)

A comprehensive and quantitative exploration of thousands of viral genomes
por: Mahmoudabadi, Gita, et al.
Publicado: (2018)

Elevation of CpG frequencies in influenza A genome attenuates pathogenicity but enhances host response to infection
por: Gaunt, Eleanor, et al.
Publicado: (2016)

MARCH8 inhibits viral infection by two different mechanisms
por: Zhang, Yanzhao, et al.
Publicado: (2020)

Host sirtuin 2 as an immunotherapeutic target against tuberculosis
por: Bhaskar, Ashima, et al.
Publicado: (2020)

Brucella activates the host RIDD pathway to subvert BLOS1-directed immune defense
por: Wells, Kelsey Michelle, et al.
Publicado: (2022)

Vibrio deploys type 2 secreted lipase to esterify cholesterol with host fatty acids and mediate cell egress
por: Chimalapati, Suneeta, et al.
Publicado: (2020)

Chitin, Chitinases and Chitinase-like Proteins in Allergic Inflammation and Tissue Remodeling
por: Lee, Chun Geun
Publicado: (2009)

RIG-like Helicase Regulation of Chitinase 3-like 1 Axis and Pulmonary Metastasis
por: Ma, Bing, et al.
Publicado: (2016)

The host exosome pathway underpins biogenesis of the human cytomegalovirus virion
por: Turner, Declan L, et al.
Publicado: (2020)

Metabolic arsenal of giant viruses: Host hijack or self-use?
por: Brahim Belhaouari, Djamal, et al.
Publicado: (2022)

Quantifying the relationship between SARS-CoV-2 viral load and infectiousness
por: Marc, Aurélien, et al.
Publicado: (2021)

Structural basis of host recognition and biofilm formation by Salmonella Saf pili
por: Zeng, Longhui, et al.
Publicado: (2017)

An intestinally secreted host factor promotes microsporidia invasion of C. elegans
por: Tamim El Jarkass, Hala, et al.
Publicado: (2022)

Cryo-electron tomography reveals novel features of a viral RNA replication compartment
por: Ertel, Kenneth J, et al.
Publicado: (2017)

Exosomes mediate horizontal transmission of viral pathogens from insect vectors to plant phloem
por: Chen, Qian, et al.
Publicado: (2021)

Principles of RNA recruitment to viral ribonucleoprotein condensates in a segmented dsRNA virus
por: Strauss, Sebastian, et al.
Publicado: (2023)

Determination of host proteins composing the microenvironment of coronavirus replicase complexes by proximity-labeling
por: V'kovski, Philip, et al.
Publicado: (2019)

Influenza A virus surface proteins are organized to help penetrate host mucus
por: Vahey, Michael D, et al.
Publicado: (2019)

Host-induced spermidine production in motile Pseudomonas aeruginosa triggers phagocytic uptake
por: Felgner, Sebastian, et al.
Publicado: (2020)

A mobile genetic element increases bacterial host fitness by manipulating development
por: Jones, Joshua M, et al.
Publicado: (2021)

The enteric pathogen Cryptosporidium parvum exports proteins into the cytosol of the infected host cell
por: Dumaine, Jennifer E, et al.
Publicado: (2021)

Acetylation of a fungal effector that translocates host PR1 facilitates virulence
por: Li, Jingtao, et al.
Publicado: (2022)

Emerging COVID-19 variants and their impact on SARS-CoV-2 diagnosis, therapeutics and vaccines
por: Fernandes, Queenie, et al.
Publicado: (2022)

Quantitative microscopy of functional HIV post-entry complexes reveals association of replication with the viral capsid
por: Peng, Ke, et al.
Publicado: (2014)

The microbiota protects from viral-induced neurologic damage through microglia-intrinsic TLR signaling
por: Brown, D Garrett, et al.
Publicado: (2019)

HIV efficiently infects T cells from the endometrium and remodels them to promote systemic viral spread
por: Ma, Tongcui, et al.
Publicado: (2020)

Initiation of HIV-1 Gag lattice assembly is required for recognition of the viral genome packaging signal
por: Lei, Xiao, et al.
Publicado: (2023)

An effector of the Irish potato famine pathogen antagonizes a host autophagy cargo receptor
por: Dagdas, Yasin F, et al.
Publicado: (2016)

An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell
por: Coffey, Michael J, et al.
Publicado: (2015)

The human leukemia virus HTLV-1 alters the structure and transcription of host chromatin in cis
por: Melamed, Anat, et al.
Publicado: (2018)

Plasmodium P36 determines host cell receptor usage during sporozoite invasion
por: Manzoni, Giulia, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ro5ig46d2o3311e67m7qb5d184