Single-cell RNA sequencing and binary hierarchical clustering define lung interstitial macrophage heterogeneity in response to hypoxia

Few studies have examined lung interstitial macrophage (IM) molecular phenotypes after being exposed to hypoxia in vivo at the single-cell level, even though macrophages contribute to hypoxic pulmonary hypertension (PH). We aimed to determine IM diversity and its association with hypoxia-induced PH....

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Detalles Bibliográficos
Autores principales: Campbell, Nzali V., Mickael, Claudia, Kumar, Sushil, Zhang, Hui, Campbell, Ian L., Gillen, Austin E., Trentin, Caio O., Diener, Katrina, Gao, Bifeng, Kheyfets, Vitaly O., Gu, Sue, Kumar, Rahul, Phang, Tzu, Brown, R. Dale, Graham, Brian B., Stenmark, Kurt R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2022
Materias:
Rapid Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273277/
https://www.ncbi.nlm.nih.gov/pubmed/35608266
http://dx.doi.org/10.1152/ajplung.00104.2022

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