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Leprosy: A Review of Epidemiology, Clinical Diagnosis, and Management
Leprosy is a neglected infectious disease caused by acid-fast bacillus Mycobacterium leprae. It primarily affects the skin and then progresses to a secondary stage, causing peripheral neuropathy with potential long-term disability along with stigma. Leprosy patients account for a significant proport...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273393/ https://www.ncbi.nlm.nih.gov/pubmed/35832335 http://dx.doi.org/10.1155/2022/8652062 |
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author | Chen, Kou-Huang Lin, Cheng-Yao Su, Shih-Bin Chen, Kow-Tong |
author_facet | Chen, Kou-Huang Lin, Cheng-Yao Su, Shih-Bin Chen, Kow-Tong |
author_sort | Chen, Kou-Huang |
collection | PubMed |
description | Leprosy is a neglected infectious disease caused by acid-fast bacillus Mycobacterium leprae. It primarily affects the skin and then progresses to a secondary stage, causing peripheral neuropathy with potential long-term disability along with stigma. Leprosy patients account for a significant proportion of the global disease burden. Previous efforts to improve diagnostic and therapeutic techniques have focused on leprosy in adults, whereas childhood leprosy has been relatively neglected. This review aims to update the diagnostic and therapeutic recommendations for adult and childhood leprosy. This review summarizes the clinical, bacteriological, and immunological approaches used in the diagnosis of leprosy. As strategies for the diagnosis and management of leprosy continue to develop better and more advanced knowledge, control and prevention of leprosy are crucial. |
format | Online Article Text |
id | pubmed-9273393 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-92733932022-07-12 Leprosy: A Review of Epidemiology, Clinical Diagnosis, and Management Chen, Kou-Huang Lin, Cheng-Yao Su, Shih-Bin Chen, Kow-Tong J Trop Med Review Article Leprosy is a neglected infectious disease caused by acid-fast bacillus Mycobacterium leprae. It primarily affects the skin and then progresses to a secondary stage, causing peripheral neuropathy with potential long-term disability along with stigma. Leprosy patients account for a significant proportion of the global disease burden. Previous efforts to improve diagnostic and therapeutic techniques have focused on leprosy in adults, whereas childhood leprosy has been relatively neglected. This review aims to update the diagnostic and therapeutic recommendations for adult and childhood leprosy. This review summarizes the clinical, bacteriological, and immunological approaches used in the diagnosis of leprosy. As strategies for the diagnosis and management of leprosy continue to develop better and more advanced knowledge, control and prevention of leprosy are crucial. Hindawi 2022-07-04 /pmc/articles/PMC9273393/ /pubmed/35832335 http://dx.doi.org/10.1155/2022/8652062 Text en Copyright © 2022 Kou-Huang Chen et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Chen, Kou-Huang Lin, Cheng-Yao Su, Shih-Bin Chen, Kow-Tong Leprosy: A Review of Epidemiology, Clinical Diagnosis, and Management |
title | Leprosy: A Review of Epidemiology, Clinical Diagnosis, and Management |
title_full | Leprosy: A Review of Epidemiology, Clinical Diagnosis, and Management |
title_fullStr | Leprosy: A Review of Epidemiology, Clinical Diagnosis, and Management |
title_full_unstemmed | Leprosy: A Review of Epidemiology, Clinical Diagnosis, and Management |
title_short | Leprosy: A Review of Epidemiology, Clinical Diagnosis, and Management |
title_sort | leprosy: a review of epidemiology, clinical diagnosis, and management |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273393/ https://www.ncbi.nlm.nih.gov/pubmed/35832335 http://dx.doi.org/10.1155/2022/8652062 |
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