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Leprosy: A Review of Epidemiology, Clinical Diagnosis, and Management

Leprosy is a neglected infectious disease caused by acid-fast bacillus Mycobacterium leprae. It primarily affects the skin and then progresses to a secondary stage, causing peripheral neuropathy with potential long-term disability along with stigma. Leprosy patients account for a significant proport...

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Detalles Bibliográficos
Autores principales: Chen, Kou-Huang, Lin, Cheng-Yao, Su, Shih-Bin, Chen, Kow-Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273393/
https://www.ncbi.nlm.nih.gov/pubmed/35832335
http://dx.doi.org/10.1155/2022/8652062
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author Chen, Kou-Huang
Lin, Cheng-Yao
Su, Shih-Bin
Chen, Kow-Tong
author_facet Chen, Kou-Huang
Lin, Cheng-Yao
Su, Shih-Bin
Chen, Kow-Tong
author_sort Chen, Kou-Huang
collection PubMed
description Leprosy is a neglected infectious disease caused by acid-fast bacillus Mycobacterium leprae. It primarily affects the skin and then progresses to a secondary stage, causing peripheral neuropathy with potential long-term disability along with stigma. Leprosy patients account for a significant proportion of the global disease burden. Previous efforts to improve diagnostic and therapeutic techniques have focused on leprosy in adults, whereas childhood leprosy has been relatively neglected. This review aims to update the diagnostic and therapeutic recommendations for adult and childhood leprosy. This review summarizes the clinical, bacteriological, and immunological approaches used in the diagnosis of leprosy. As strategies for the diagnosis and management of leprosy continue to develop better and more advanced knowledge, control and prevention of leprosy are crucial.
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spelling pubmed-92733932022-07-12 Leprosy: A Review of Epidemiology, Clinical Diagnosis, and Management Chen, Kou-Huang Lin, Cheng-Yao Su, Shih-Bin Chen, Kow-Tong J Trop Med Review Article Leprosy is a neglected infectious disease caused by acid-fast bacillus Mycobacterium leprae. It primarily affects the skin and then progresses to a secondary stage, causing peripheral neuropathy with potential long-term disability along with stigma. Leprosy patients account for a significant proportion of the global disease burden. Previous efforts to improve diagnostic and therapeutic techniques have focused on leprosy in adults, whereas childhood leprosy has been relatively neglected. This review aims to update the diagnostic and therapeutic recommendations for adult and childhood leprosy. This review summarizes the clinical, bacteriological, and immunological approaches used in the diagnosis of leprosy. As strategies for the diagnosis and management of leprosy continue to develop better and more advanced knowledge, control and prevention of leprosy are crucial. Hindawi 2022-07-04 /pmc/articles/PMC9273393/ /pubmed/35832335 http://dx.doi.org/10.1155/2022/8652062 Text en Copyright © 2022 Kou-Huang Chen et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Chen, Kou-Huang
Lin, Cheng-Yao
Su, Shih-Bin
Chen, Kow-Tong
Leprosy: A Review of Epidemiology, Clinical Diagnosis, and Management
title Leprosy: A Review of Epidemiology, Clinical Diagnosis, and Management
title_full Leprosy: A Review of Epidemiology, Clinical Diagnosis, and Management
title_fullStr Leprosy: A Review of Epidemiology, Clinical Diagnosis, and Management
title_full_unstemmed Leprosy: A Review of Epidemiology, Clinical Diagnosis, and Management
title_short Leprosy: A Review of Epidemiology, Clinical Diagnosis, and Management
title_sort leprosy: a review of epidemiology, clinical diagnosis, and management
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273393/
https://www.ncbi.nlm.nih.gov/pubmed/35832335
http://dx.doi.org/10.1155/2022/8652062
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