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A Nationwide Study on the Seroprevalence of Measles, Mumps, and Rubella in Iranian Children and Adolescents
BACKGROUND: Assessing the prevalence of infections, which are preventable by vaccination, is crucial to monitor the vaccination program efficacy, and it can demonstrate the gaps in population immunity. The current study attempted to assess the specific Immunoglobulin (IgG) antibody against measles,...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Tehran University of Medical Sciences
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273495/ https://www.ncbi.nlm.nih.gov/pubmed/35866127 http://dx.doi.org/10.18502/ijph.v51i2.8694 |
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author | Nokhodian, Zary Ataei, Behrooz Gouya, Mohammad Mehdi Ghaffari Hoseini, Shervin Yaran, Majid Mansourian, Marjan Motlagh, Mohammad Esmaeil Heshmat, Ramin Zahraei, Seyed Mohsen Kelishadi, Roya |
author_facet | Nokhodian, Zary Ataei, Behrooz Gouya, Mohammad Mehdi Ghaffari Hoseini, Shervin Yaran, Majid Mansourian, Marjan Motlagh, Mohammad Esmaeil Heshmat, Ramin Zahraei, Seyed Mohsen Kelishadi, Roya |
author_sort | Nokhodian, Zary |
collection | PubMed |
description | BACKGROUND: Assessing the prevalence of infections, which are preventable by vaccination, is crucial to monitor the vaccination program efficacy, and it can demonstrate the gaps in population immunity. The current study attempted to assess the specific Immunoglobulin (IgG) antibody against measles, mumps, and rubella (MMR) in Iranian children and adolescents, years after their vaccination. METHODS: This cross-sectional study was conducted in Iran. Serum samples of 2100 students, aged 7–18 years, included in a national health survey, were tested for MMR antibodies by ELISA assay. Multistage random cluster sampling was used to select subjects from 30 provinces in Iran. RESULTS: Overall, 1871, 1718, and 1678 serums were tested for measles, mumps, and rubella antibodies, respectively. The prevalence of positive test was 1231 (65.8%) for measles, 1327 (77.2%) for mumps and 1344 (80.1%) for rubella. CONCLUSION: Despite high vaccination coverage in Iran, IgG antibody against measles, mumps, and rubella was not detected in a considerable proportion of children and adolescents aged 7–18 years. In case of contacts with residents of other countries, where measles or rubella have not yet been eliminated, it may create problems for Iranian children. |
format | Online Article Text |
id | pubmed-9273495 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Tehran University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-92734952022-07-20 A Nationwide Study on the Seroprevalence of Measles, Mumps, and Rubella in Iranian Children and Adolescents Nokhodian, Zary Ataei, Behrooz Gouya, Mohammad Mehdi Ghaffari Hoseini, Shervin Yaran, Majid Mansourian, Marjan Motlagh, Mohammad Esmaeil Heshmat, Ramin Zahraei, Seyed Mohsen Kelishadi, Roya Iran J Public Health Original Article BACKGROUND: Assessing the prevalence of infections, which are preventable by vaccination, is crucial to monitor the vaccination program efficacy, and it can demonstrate the gaps in population immunity. The current study attempted to assess the specific Immunoglobulin (IgG) antibody against measles, mumps, and rubella (MMR) in Iranian children and adolescents, years after their vaccination. METHODS: This cross-sectional study was conducted in Iran. Serum samples of 2100 students, aged 7–18 years, included in a national health survey, were tested for MMR antibodies by ELISA assay. Multistage random cluster sampling was used to select subjects from 30 provinces in Iran. RESULTS: Overall, 1871, 1718, and 1678 serums were tested for measles, mumps, and rubella antibodies, respectively. The prevalence of positive test was 1231 (65.8%) for measles, 1327 (77.2%) for mumps and 1344 (80.1%) for rubella. CONCLUSION: Despite high vaccination coverage in Iran, IgG antibody against measles, mumps, and rubella was not detected in a considerable proportion of children and adolescents aged 7–18 years. In case of contacts with residents of other countries, where measles or rubella have not yet been eliminated, it may create problems for Iranian children. Tehran University of Medical Sciences 2022-02 /pmc/articles/PMC9273495/ /pubmed/35866127 http://dx.doi.org/10.18502/ijph.v51i2.8694 Text en Copyright © 2022 Nokhodian et al. Published by Tehran University of Medical Sciences https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International license (https://creativecommons.org/licenses/by-nc/4.0/). Non-commercial uses of the work are permitted, provided the original work is properly cited. |
spellingShingle | Original Article Nokhodian, Zary Ataei, Behrooz Gouya, Mohammad Mehdi Ghaffari Hoseini, Shervin Yaran, Majid Mansourian, Marjan Motlagh, Mohammad Esmaeil Heshmat, Ramin Zahraei, Seyed Mohsen Kelishadi, Roya A Nationwide Study on the Seroprevalence of Measles, Mumps, and Rubella in Iranian Children and Adolescents |
title | A Nationwide Study on the Seroprevalence of Measles, Mumps, and Rubella in Iranian Children and Adolescents |
title_full | A Nationwide Study on the Seroprevalence of Measles, Mumps, and Rubella in Iranian Children and Adolescents |
title_fullStr | A Nationwide Study on the Seroprevalence of Measles, Mumps, and Rubella in Iranian Children and Adolescents |
title_full_unstemmed | A Nationwide Study on the Seroprevalence of Measles, Mumps, and Rubella in Iranian Children and Adolescents |
title_short | A Nationwide Study on the Seroprevalence of Measles, Mumps, and Rubella in Iranian Children and Adolescents |
title_sort | nationwide study on the seroprevalence of measles, mumps, and rubella in iranian children and adolescents |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273495/ https://www.ncbi.nlm.nih.gov/pubmed/35866127 http://dx.doi.org/10.18502/ijph.v51i2.8694 |
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