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Acute disseminated encephalomyelitis (ADEM) following SARS-CoV-2 infection: A case report from Iran

The new coronavirus disease 2019 (COVID-19) outbreak has rapidly spread throughout the world, becoming a serious public health problem. COVID-19, in addition to respiratory symptoms, has neurotropic characteristics that can impact the nervous system. We present a 22-year-old female who developed dip...

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Autores principales: Asadollahzade, Elnaz, Azhdari, Sara, Johari, Mohammed-Sadegh, Naser Moghadasi, Abdorreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier España, S.L.U. on behalf of Sociedad Española de Enfermería Neurológica. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273525/
http://dx.doi.org/10.1016/j.sedene.2022.06.003
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author Asadollahzade, Elnaz
Azhdari, Sara
Johari, Mohammed-Sadegh
Naser Moghadasi, Abdorreza
author_facet Asadollahzade, Elnaz
Azhdari, Sara
Johari, Mohammed-Sadegh
Naser Moghadasi, Abdorreza
author_sort Asadollahzade, Elnaz
collection PubMed
description The new coronavirus disease 2019 (COVID-19) outbreak has rapidly spread throughout the world, becoming a serious public health problem. COVID-19, in addition to respiratory symptoms, has neurotropic characteristics that can impact the nervous system. We present a 22-year-old female who developed diplopia and numbness of her limbs eight days after affecting by COVID-19 and she showed a left-sided outward gaze palsy without any history of previous a specific illness or medication. Supratentorial, infratentorial, and cervical cord enhancing plaques confirmed an acute demyelinating process in favor of Acute disseminated encephalomyelitis (ADEM). Her oligoclonal bands (OCB) were positive as well. As a result, a provisional diagnosis of ADEM was made. Her condition improved dramatically after starting corticosteroids and rituximab.
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spelling pubmed-92735252022-07-12 Acute disseminated encephalomyelitis (ADEM) following SARS-CoV-2 infection: A case report from Iran Asadollahzade, Elnaz Azhdari, Sara Johari, Mohammed-Sadegh Naser Moghadasi, Abdorreza Revista Cienti´fica De La Sociedad Espan~ola De Enfermeri´a Neurolo´gica Case Report The new coronavirus disease 2019 (COVID-19) outbreak has rapidly spread throughout the world, becoming a serious public health problem. COVID-19, in addition to respiratory symptoms, has neurotropic characteristics that can impact the nervous system. We present a 22-year-old female who developed diplopia and numbness of her limbs eight days after affecting by COVID-19 and she showed a left-sided outward gaze palsy without any history of previous a specific illness or medication. Supratentorial, infratentorial, and cervical cord enhancing plaques confirmed an acute demyelinating process in favor of Acute disseminated encephalomyelitis (ADEM). Her oligoclonal bands (OCB) were positive as well. As a result, a provisional diagnosis of ADEM was made. Her condition improved dramatically after starting corticosteroids and rituximab. Published by Elsevier España, S.L.U. on behalf of Sociedad Española de Enfermería Neurológica. 2022-07-12 /pmc/articles/PMC9273525/ http://dx.doi.org/10.1016/j.sedene.2022.06.003 Text en © 2022 Published by Elsevier España, S.L.U. on behalf of Sociedad Española de Enfermería Neurológica. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Case Report
Asadollahzade, Elnaz
Azhdari, Sara
Johari, Mohammed-Sadegh
Naser Moghadasi, Abdorreza
Acute disseminated encephalomyelitis (ADEM) following SARS-CoV-2 infection: A case report from Iran
title Acute disseminated encephalomyelitis (ADEM) following SARS-CoV-2 infection: A case report from Iran
title_full Acute disseminated encephalomyelitis (ADEM) following SARS-CoV-2 infection: A case report from Iran
title_fullStr Acute disseminated encephalomyelitis (ADEM) following SARS-CoV-2 infection: A case report from Iran
title_full_unstemmed Acute disseminated encephalomyelitis (ADEM) following SARS-CoV-2 infection: A case report from Iran
title_short Acute disseminated encephalomyelitis (ADEM) following SARS-CoV-2 infection: A case report from Iran
title_sort acute disseminated encephalomyelitis (adem) following sars-cov-2 infection: a case report from iran
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273525/
http://dx.doi.org/10.1016/j.sedene.2022.06.003
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