Blocking glycine utilization inhibits multiple myeloma progression by disrupting glutathione balance

Metabolites in the tumor microenvironment are a critical factor for tumor progression. However, the lack of knowledge about the metabolic profile in the bone marrow (BM) microenvironment of multiple myeloma (MM) limits our understanding of MM progression. Here, we show that the glycine concentration...

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Detalles Bibliográficos
Autores principales: Xia, Jiliang, Zhang, Jingyu, Wu, Xuan, Du, Wanqing, Zhu, Yinghong, Liu, Xing, Liu, Zhenhao, Meng, Bin, Guo, Jiaojiao, Yang, Qin, Wang, Yihui, Wang, Qinglin, Feng, Xiangling, Xie, Guoxiang, Shen, Yi, He, Yanjuan, Xiang, Juanjuan, Wu, Minghua, An, Gang, Qiu, Lugui, Jia, Wei, Zhou, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273595/
https://www.ncbi.nlm.nih.gov/pubmed/35817773
http://dx.doi.org/10.1038/s41467-022-31248-w

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