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Translational fidelity and growth of Arabidopsis require stress-sensitive diphthamide biosynthesis

Diphthamide, a post-translationally modified histidine residue of eukaryotic TRANSLATION ELONGATION FACTOR2 (eEF2), is the human host cell-sensitizing target of diphtheria toxin. Diphthamide biosynthesis depends on the 4Fe-4S-cluster protein Dph1 catalyzing the first committed step, as well as Dph2...

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Detalles Bibliográficos
Autores principales:	Zhang, Hongliang, Quintana, Julia, Ütkür, Koray, Adrian, Lorenz, Hawer, Harmen, Mayer, Klaus, Gong, Xiaodi, Castanedo, Leonardo, Schulten, Anna, Janina, Nadežda, Peters, Marcus, Wirtz, Markus, Brinkmann, Ulrich, Schaffrath, Raffael, Krämer, Ute
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273596/ https://www.ncbi.nlm.nih.gov/pubmed/35817801 http://dx.doi.org/10.1038/s41467-022-31712-7

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