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Simple gene signature to assess murine fibroblast polarization

We provide an original multi-stage approach identifying a gene signature to assess murine fibroblast polarization. Prototypic polarizations (inflammatory/fibrotic) were induced by seeded mouse embryonic fibroblasts (MEFs) with TNFα or TGFß1, respectively. The transcriptomic and proteomic profiles we...

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Detalles Bibliográficos
Autores principales: Ledoult, Emmanuel, Jendoubi, Manel, Collet, Aurore, Guerrier, Thomas, Largy, Alexis, Speca, Silvia, Vivier, Solange, Bray, Fabrice, Figeac, Martin, Hachulla, Eric, Labalette, Myriam, Leprêtre, Frédéric, Sebda, Shéhérazade, Sanges, Sébastien, Rolando, Christian, Sobanski, Vincent, Dubucquoi, Sylvain, Launay, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273630/
https://www.ncbi.nlm.nih.gov/pubmed/35817787
http://dx.doi.org/10.1038/s41598-022-15640-6