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Cellular Tolerance Induced by Chronic Opioids in the Central Nervous System

Opioids are powerful analgesics that elicit acute antinociceptive effects through their action the mu opioid receptor (MOR). However opioids are ineffective for chronic pain management, in part because continuous activation of MORs induces adaptive changes at the receptor level and downstream signal...

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Detalles Bibliográficos
Autores principales:	Adhikary, Sweta, Williams, John T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273719/ https://www.ncbi.nlm.nih.gov/pubmed/35837149 http://dx.doi.org/10.3389/fnsys.2022.937126

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