Cargando…

Reinventing positive-strand RNA virus reverse genetics

Reverse genetics is the prospective analysis of how genotype determines phenotype. In a typical experiment, a researcher alters a viral genome, then observes the phenotypic outcome. Among RNA viruses, this approach was first applied to positive-strand RNA viruses in the mid-1970s and over nearly 50...

Descripción completa

Detalles Bibliográficos
Autor principal: Lindenbach, Brett D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273853/
https://www.ncbi.nlm.nih.gov/pubmed/35840179
http://dx.doi.org/10.1016/bs.aivir.2022.03.001