Latent Autoimmune Diabetes in Adults and Metabolic Syndrome—A Mini Review

Latent autoimmune diabetes in adults (LADA) is a heterogeneous subtype of diabetes characterized by islet cell destruction mediated by islet autoimmunity and insulin resistance. Metabolic syndrome (MetS) is a state in which many risk factors for metabolic and cardiovascular diseases accumulate in an...

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Detalles Bibliográficos
Autores principales: Pan, Niansi, Yang, Shimei, Niu, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273866/
https://www.ncbi.nlm.nih.gov/pubmed/35837301
http://dx.doi.org/10.3389/fendo.2022.913373
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author Pan, Niansi
Yang, Shimei
Niu, Xiaohong
author_facet Pan, Niansi
Yang, Shimei
Niu, Xiaohong
author_sort Pan, Niansi
collection PubMed
description Latent autoimmune diabetes in adults (LADA) is a heterogeneous subtype of diabetes characterized by islet cell destruction mediated by islet autoimmunity and insulin resistance. Metabolic syndrome (MetS) is a state in which many risk factors for metabolic and cardiovascular diseases accumulate in an individual. Based on clinical data, this review covers the prevalence of MetS in LADA, focusing on the risk associated with and the role of insulin resistance in the development of LADA from the perspective of inflammatory factors, environmental factors, and the gut microbiota, aiming to improve our understanding of this condition.
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spelling pubmed-92738662022-07-13 Latent Autoimmune Diabetes in Adults and Metabolic Syndrome—A Mini Review Pan, Niansi Yang, Shimei Niu, Xiaohong Front Endocrinol (Lausanne) Endocrinology Latent autoimmune diabetes in adults (LADA) is a heterogeneous subtype of diabetes characterized by islet cell destruction mediated by islet autoimmunity and insulin resistance. Metabolic syndrome (MetS) is a state in which many risk factors for metabolic and cardiovascular diseases accumulate in an individual. Based on clinical data, this review covers the prevalence of MetS in LADA, focusing on the risk associated with and the role of insulin resistance in the development of LADA from the perspective of inflammatory factors, environmental factors, and the gut microbiota, aiming to improve our understanding of this condition. Frontiers Media S.A. 2022-06-28 /pmc/articles/PMC9273866/ /pubmed/35837301 http://dx.doi.org/10.3389/fendo.2022.913373 Text en Copyright © 2022 Pan, Yang and Niu https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Pan, Niansi
Yang, Shimei
Niu, Xiaohong
Latent Autoimmune Diabetes in Adults and Metabolic Syndrome—A Mini Review
title Latent Autoimmune Diabetes in Adults and Metabolic Syndrome—A Mini Review
title_full Latent Autoimmune Diabetes in Adults and Metabolic Syndrome—A Mini Review
title_fullStr Latent Autoimmune Diabetes in Adults and Metabolic Syndrome—A Mini Review
title_full_unstemmed Latent Autoimmune Diabetes in Adults and Metabolic Syndrome—A Mini Review
title_short Latent Autoimmune Diabetes in Adults and Metabolic Syndrome—A Mini Review
title_sort latent autoimmune diabetes in adults and metabolic syndrome—a mini review
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273866/
https://www.ncbi.nlm.nih.gov/pubmed/35837301
http://dx.doi.org/10.3389/fendo.2022.913373
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