TP53 Mutations Identified Using NGS Comprise the Overwhelming Majority of TP53 Disruptions in CLL: Results From a Multicentre Study

Limited data exists to show the correlation of (tumour protein 53) TP53 mutation detected by Next generation sequencing (NGS) and the presence/absence of deletions of 17p13 detected by FISH. The study which is the largest series to date includes 2332 CLL patients referred for analysis of del(17p) by...

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Detalles Bibliográficos
Autores principales: Catherwood, Mark A., Wren, Dorte, Chiecchio, Laura, Cavalieri, Doriane, Donaldson, David, Lawless, Sarah, ElHassadi, Ezzat, Hayat, Amjad, Cahill, Mary R., O’Shea, Derville, Sargent, Jeremy, Stewart, Peter, Maurya, Manisha, Quinn, John, Murphy, Philip, de Castro, David Gonzalez, Mills, Ken, Cross, Nicholas C. P., Forconi, Francesco, Iyengar, Sunil, Schuh, Anna, Thornton, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273895/
https://www.ncbi.nlm.nih.gov/pubmed/35837095
http://dx.doi.org/10.3389/fonc.2022.909615

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