Induction of Trained Immunity Protects Neonatal Mice Against Microbial Sepsis by Boosting Both the Inflammatory Response and Antimicrobial Activity

BACKGROUND: Neonates are susceptible to a wide range of microbial infection and at a high risk to develop severe sepsis and septic shock. Emerged evidence has shown that induction of trained immunity triggers a much stronger inflammatory response in adult monocytes/macrophages, thereby conferring pr...

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Detalles Bibliográficos
Autores principales: Zhou, Huiting, Lu, Xiaying, Huang, Jie, Jordan, Patrick, Ma, Shurong, Xu, Lingqi, Hu, Fangjie, Gui, Huan, Zhao, He, Bai, Zhenjiang, Redmond, H Paul, Wang, Jiang Huai, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273902/
https://www.ncbi.nlm.nih.gov/pubmed/35836719
http://dx.doi.org/10.2147/JIR.S363995

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