Cargando…
Mambalgin-2 Inhibits Lung Adenocarcinoma Growth and Migration by Selective Interaction With ASIC1/α-ENaC/γ-ENaC Heterotrimer
Lung cancer is one of the most common cancer types in the world. Despite existing treatment strategies, overall patient survival remains low and new targeted therapies are required. Acidification of the tumor microenvironment drives the growth and metastasis of many cancers. Acid sensors such as aci...
Autores principales: | Sudarikova, Anastasia V., Bychkov, Maxim L., Kulbatskii, Dmitrii S., Chubinskiy-Nadezhdin, Vladislav I., Shlepova, Olga V., Shulepko, Mikhail A., Koshelev, Sergey G., Kirpichnikov, Mikhail P., Lyukmanova, Ekaterina N. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273970/ https://www.ncbi.nlm.nih.gov/pubmed/35837090 http://dx.doi.org/10.3389/fonc.2022.904742 |
Ejemplares similares
-
Molecular Basis for Mambalgin-2 Interaction with Heterotrimeric α-ENaC/ASIC1a/γ-ENaC Channels in Cancer Cells
por: Lyukmanova, Ekaterina N., et al.
Publicado: (2023) -
The N terminus of α-ENaC mediates ENaC cleavage and activation by furin
por: Kota, Pradeep, et al.
Publicado: (2018) -
ENaC activation by proteases
por: Anand, Deepika, et al.
Publicado: (2022) -
ENaC in Cholinergic Brush Cells
por: Kandel, Chrissy, et al.
Publicado: (2018) -
Expression of ENaC subunits in epithelia
por: Frindt, Gustavo, et al.
Publicado: (2022)