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Molecular Modeling of ABHD5 Structure and Ligand Recognition

Alpha/beta hydrolase domain-containing 5 (ABHD5), also termed CGI-58, is the key upstream activator of adipose triglyceride lipase (ATGL), which plays an essential role in lipid metabolism and energy storage. Mutations in ABHD5 disrupt lipolysis and are known to cause the Chanarin-Dorfman syndrome....

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Detalles Bibliográficos
Autores principales:	Shahoei, Rezvan, Pangeni, Susheel, Sanders, Matthew A., Zhang, Huamei, Mladenovic-Lucas, Ljiljana, Roush, William R., Halvorsen, Geoff, Kelly, Christopher V., Granneman, James G., Huang, Yu-ming M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274090/ https://www.ncbi.nlm.nih.gov/pubmed/35836935 http://dx.doi.org/10.3389/fmolb.2022.935375

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