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MST4 negatively regulates type I interferons production via targeting MAVS-mediated pathway

BACKGROUND: Cytosolic RNA sensing can elicit immune responses against viral pathogens. However, antiviral responses must be tightly regulated to avoid the uncontrolled production of type I interferons (IFN) that might have deleterious effects on the host. Upon bacterial infection, the germinal cente...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Ma, Zhenling, Wu, Yaru, Yuan, Cui, Zhang, Yanyan, Liang, Zeyang, Yang, Yu, Zhang, Wenwen, Jiao, Pengtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274187/
https://www.ncbi.nlm.nih.gov/pubmed/35820905
http://dx.doi.org/10.1186/s12964-022-00922-3