DDX3 acts as a tumor suppressor in colorectal cancer as loss of DDX3 in advanced cancer promotes tumor progression by activating the MAPK pathway

Objective: The treatment and prognosis of patients with advanced colorectal cancer (CRC) remain a difficult problem. Herein, we investigated the role of DEAD (Asp-Glu-Ala-Asp) box helicase 3 (DDX3) in CRC and proposed potential therapeutic targets for advanced CRC. Methods: The expression of DDX3 in...

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Detalles Bibliográficos
Autores principales: Shen, Lin, Zhang, Jing, Xu, Meng, Zheng, Ying, Wang, Mo, Yang, Suzhen, Qin, Bin, Li, Shunle, Dong, Lei, Dai, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274493/
https://www.ncbi.nlm.nih.gov/pubmed/35844798
http://dx.doi.org/10.7150/ijbs.73491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274493/
https://www.ncbi.nlm.nih.gov/pubmed/35844798
http://dx.doi.org/10.7150/ijbs.73491

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