A positive feedback loop of CENPU/E2F6/E2F1 facilitates proliferation and metastasis via ubiquitination of E2F6 in hepatocellular carcinoma

Centromere protein U (CENPU), a centromere-binding protein required for cellular mitosis, has been reported to be closely associated with carcinogenesis in multiple malignancies; however, the role of CENPU in hepatocellular carcinoma (HCC) is still unclear. Herein, we investigated its biological rol...

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Detalles Bibliográficos
Autores principales: Liu, Yingyi, Yao, Ye, Liao, Bo, Zhang, Hao, Yang, Zhangshuo, Xia, Peng, Jiang, Xiang, Ma, Weijie, Wu, Xiaoling, Mei, Chengjie, Wang, Ganggang, Gao, Meng, Xu, Kequan, GongYe, Xiangdong, Cheng, Zhixiang, Jiang, Ping, Chen, Xi, Yuan, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274498/
https://www.ncbi.nlm.nih.gov/pubmed/35844791
http://dx.doi.org/10.7150/ijbs.69495

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