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Integrated multi-omics characterization of KRAS mutant colorectal cancer

KRAS mutation is the most frequent oncogenic aberration in colorectal cancer (CRC). The molecular mechanism and clinical implications of KRAS mutation in CRC remain unclear and show high heterogeneity within these tumors. Methods: We harnessed the multi-omics data (genomic, transcriptomic, proteomic...

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Detalles Bibliográficos
Autores principales: Chong, Wei, Zhu, Xingyu, Ren, Huicheng, Ye, Chunshui, Xu, Kang, Wang, Zhe, Jia, Shengtao, Shang, Liang, Li, Leping, Chen, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274732/
https://www.ncbi.nlm.nih.gov/pubmed/35836817
http://dx.doi.org/10.7150/thno.73089

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