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Integrated multi-omics characterization of KRAS mutant colorectal cancer
KRAS mutation is the most frequent oncogenic aberration in colorectal cancer (CRC). The molecular mechanism and clinical implications of KRAS mutation in CRC remain unclear and show high heterogeneity within these tumors. Methods: We harnessed the multi-omics data (genomic, transcriptomic, proteomic...
Autores principales: | Chong, Wei, Zhu, Xingyu, Ren, Huicheng, Ye, Chunshui, Xu, Kang, Wang, Zhe, Jia, Shengtao, Shang, Liang, Li, Leping, Chen, Hao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274732/ https://www.ncbi.nlm.nih.gov/pubmed/35836817 http://dx.doi.org/10.7150/thno.73089 |
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