Loss of MLKL ameliorates liver fibrosis by inhibiting hepatocyte necroptosis and hepatic stellate cell activation

Background: Liver fibrosis affects millions of people worldwide without an effective treatment. Although multiple cell types in the liver contribute to the fibrogenic process, hepatocyte death is considered to be the trigger. Multiple forms of cell death, including necrosis, apoptosis, and necroptos...

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Detalles Bibliográficos
Autores principales: Guo, Ren, Jia, Xiaohui, Ding, Zhenbin, Wang, Gang, Jiang, Mengmeng, Li, Bing, Chen, Shanshan, Xia, Bingqing, Zhang, Qing, Liu, Jian, Zheng, Ruting, Gao, Zhaobing, Xie, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274737/
https://www.ncbi.nlm.nih.gov/pubmed/35836819
http://dx.doi.org/10.7150/thno.71400

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