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UBR5 promotes tumor immune evasion through enhancing IFN-γ-induced PDL1 transcription in triple negative breast cancer

Background: The up-regulation of PD-L1 is recognized as an adaption of cancer cells to evade immune surveillance and attack. However, the intrinsic mechanisms of the induction of PD-L1 by interferon-γ (IFN-γ) in tumor microenvironment remain incompletely characterized. Ubiquitin ligase E3 component...

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Detalles Bibliográficos
Autores principales:	Wu, Bingbing, Song, Mei, Dong, Qun, Xiang, Gang, Li, Jing, Ma, Xiaojing, Wei, Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274738/ https://www.ncbi.nlm.nih.gov/pubmed/35836797 http://dx.doi.org/10.7150/thno.74989

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