Stress-induced premature senescence is associated with a prolonged QT interval and recapitulates features of cardiac aging

Rationale: Aging in the heart is a gradual process, involving continuous changes in cardiovascular cells, including cardiomyocytes (CMs), namely cellular senescence. These changes finally lead to adverse organ remodeling and resulting in heart failure. This study exploits CMs from human induced plur...

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Detalles Bibliográficos
Autores principales: Lazzarini, Edoardo, Lodrini, Alessandra Maria, Arici, Martina, Bolis, Sara, Vagni, Sara, Panella, Stefano, Rendon-Angel, Azucena, Saibene, Melissa, Metallo, Alessia, Torre, Tiziano, Vassalli, Giuseppe, Ameri, Pietro, Altomare, Claudia, Rocchetti, Marcella, Barile, Lucio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274748/
https://www.ncbi.nlm.nih.gov/pubmed/35836799
http://dx.doi.org/10.7150/thno.70884

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