Massively Parallel Sequencing of the Filaggrin Gene Reveals an Association Between FLG Loss-of-function Mutations and Leprosy

Filaggrin, encoded by the FLG gene, plays a crucial role in the barrier function of epidermis, but the association between FLG loss-of-function mutations and infectious skin diseases has not been systematically studied. FLG coding sequences from 945 patients with leprosy and 916 healthy controls wer...

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Detalles Bibliográficos
Autores principales: SHI, Wenhao, MI, Zihao, WANG, Zhenzhen, ZHANG, Huimin, WANG, Na, WANG, Zhe, ZHANG, Bowen, XIA, Qianqian, YU, Yueqian, YU, Gongqi, SUN, Lele, FU, Xi’an, WANG, Chuan, LIU, Hong, ZHANG, Furen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Publication of Acta Dermato-Venereologica 2020
Materias:
Investigative Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274930/
https://www.ncbi.nlm.nih.gov/pubmed/33047146
http://dx.doi.org/10.2340/00015555-3663

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