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A human IgM enriched immunoglobulin preparation, Pentaglobin, reverses autoimmune diabetes without immune suppression in NOD mice

The immune system of healthy individuals is capable of regulating autoimmunity through multiple mechanisms. In Type 1 Diabetes (T1D) we recently discovered natural IgM, although present at normal levels, is unable to perform its normal immunoregulatory function. Treating diabetic mice with IgM from...

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Detalles Bibliográficos
Autores principales:	Wilson, Christopher S., Hoopes, Emilee M., Falk, Alexander C., Moore, Daniel J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274958/ https://www.ncbi.nlm.nih.gov/pubmed/35821261 http://dx.doi.org/10.1038/s41598-022-15676-8

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