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Lung Cancer with Brain Metastases Treated with Radiotherapy Followed by Bevacizumab Maintenance: A Case Report

Brain metastases in a patient with non-small cell lung cancer carry a grave prognosis. Without effective interventions, the average survival rate is 6 months. Here, we present a case of a 59-year-old male with non-small cell lung cancer and multiple brain metastases treated with radiotherapy followe...

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Autores principales: Khan, Sajjad Ahmed, Gautam, Sakshyam, Sapkota, Sulav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of the Nepal Medical Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275467/
https://www.ncbi.nlm.nih.gov/pubmed/35690983
http://dx.doi.org/10.31729/jnma.7400
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author Khan, Sajjad Ahmed
Gautam, Sakshyam
Sapkota, Sulav
author_facet Khan, Sajjad Ahmed
Gautam, Sakshyam
Sapkota, Sulav
author_sort Khan, Sajjad Ahmed
collection PubMed
description Brain metastases in a patient with non-small cell lung cancer carry a grave prognosis. Without effective interventions, the average survival rate is 6 months. Here, we present a case of a 59-year-old male with non-small cell lung cancer and multiple brain metastases treated with radiotherapy followed by bevacizumab maintenance with prolonged survival. There are limited studies establishing the efficiency and toxicity profile of anti-vascular endothelial growth factors for brain metastases. This reported case had a remarkable response with marked clinical and radiological improvement along with a tolerable toxicity profile. Showing the extent of effectiveness and efficacy of anti-vascular endothelial growth factor agents in the case of lung cancer with brain metastases is the main motto of our study.
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spelling pubmed-92754672023-02-08 Lung Cancer with Brain Metastases Treated with Radiotherapy Followed by Bevacizumab Maintenance: A Case Report Khan, Sajjad Ahmed Gautam, Sakshyam Sapkota, Sulav JNMA J Nepal Med Assoc Case Report Brain metastases in a patient with non-small cell lung cancer carry a grave prognosis. Without effective interventions, the average survival rate is 6 months. Here, we present a case of a 59-year-old male with non-small cell lung cancer and multiple brain metastases treated with radiotherapy followed by bevacizumab maintenance with prolonged survival. There are limited studies establishing the efficiency and toxicity profile of anti-vascular endothelial growth factors for brain metastases. This reported case had a remarkable response with marked clinical and radiological improvement along with a tolerable toxicity profile. Showing the extent of effectiveness and efficacy of anti-vascular endothelial growth factor agents in the case of lung cancer with brain metastases is the main motto of our study. Journal of the Nepal Medical Association 2022-06 2022-06-30 /pmc/articles/PMC9275467/ /pubmed/35690983 http://dx.doi.org/10.31729/jnma.7400 Text en © The Author(s) 2018. https://creativecommons.org/licenses/by/4.0/This is an Open-Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Khan, Sajjad Ahmed
Gautam, Sakshyam
Sapkota, Sulav
Lung Cancer with Brain Metastases Treated with Radiotherapy Followed by Bevacizumab Maintenance: A Case Report
title Lung Cancer with Brain Metastases Treated with Radiotherapy Followed by Bevacizumab Maintenance: A Case Report
title_full Lung Cancer with Brain Metastases Treated with Radiotherapy Followed by Bevacizumab Maintenance: A Case Report
title_fullStr Lung Cancer with Brain Metastases Treated with Radiotherapy Followed by Bevacizumab Maintenance: A Case Report
title_full_unstemmed Lung Cancer with Brain Metastases Treated with Radiotherapy Followed by Bevacizumab Maintenance: A Case Report
title_short Lung Cancer with Brain Metastases Treated with Radiotherapy Followed by Bevacizumab Maintenance: A Case Report
title_sort lung cancer with brain metastases treated with radiotherapy followed by bevacizumab maintenance: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275467/
https://www.ncbi.nlm.nih.gov/pubmed/35690983
http://dx.doi.org/10.31729/jnma.7400
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AT sapkotasulav lungcancerwithbrainmetastasestreatedwithradiotherapyfollowedbybevacizumabmaintenanceacasereport