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CNS Lymphoma: Clinical Pearls and Management Considerations
Primary CNS lymphoma presents unique challenges for the clinician. New evidence has emerged regarding the appropriate workup, management considerations, and treatment. In this paper, we highlight the clinical presentations, disease prognosis, and management considerations. We place specific emphasis...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275513/ https://www.ncbi.nlm.nih.gov/pubmed/35832688 |
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author | Michel, Michelot Lucke-Wold, Noelle Hosseini, Mohammad Reza Panther, Eric Reddy, Ramya Lucke-Wold, Brandon |
author_facet | Michel, Michelot Lucke-Wold, Noelle Hosseini, Mohammad Reza Panther, Eric Reddy, Ramya Lucke-Wold, Brandon |
author_sort | Michel, Michelot |
collection | PubMed |
description | Primary CNS lymphoma presents unique challenges for the clinician. New evidence has emerged regarding the appropriate workup, management considerations, and treatment. In this paper, we highlight the clinical presentations, disease prognosis, and management considerations. We place specific emphasis on the decision tree for immunocompetent and immunocompromised. The key imaging characteristics are discussed. Once biopsy prove lymphoma, important management considerations are addressed. We highlight need for follow up and role for surgery verse radiation. Finally, we present emerging treatment options and pre-clinical work that will be making its way through the pipeline. This up-to-date review will serve as a key learning tool for clinicians and researchers |
format | Online Article Text |
id | pubmed-9275513 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
record_format | MEDLINE/PubMed |
spelling | pubmed-92755132022-07-12 CNS Lymphoma: Clinical Pearls and Management Considerations Michel, Michelot Lucke-Wold, Noelle Hosseini, Mohammad Reza Panther, Eric Reddy, Ramya Lucke-Wold, Brandon Biomed Res Clin Rev Article Primary CNS lymphoma presents unique challenges for the clinician. New evidence has emerged regarding the appropriate workup, management considerations, and treatment. In this paper, we highlight the clinical presentations, disease prognosis, and management considerations. We place specific emphasis on the decision tree for immunocompetent and immunocompromised. The key imaging characteristics are discussed. Once biopsy prove lymphoma, important management considerations are addressed. We highlight need for follow up and role for surgery verse radiation. Finally, we present emerging treatment options and pre-clinical work that will be making its way through the pipeline. This up-to-date review will serve as a key learning tool for clinicians and researchers 2022 2022-06-27 /pmc/articles/PMC9275513/ /pubmed/35832688 Text en https://creativecommons.org/licenses/by/4.0/this is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Article Michel, Michelot Lucke-Wold, Noelle Hosseini, Mohammad Reza Panther, Eric Reddy, Ramya Lucke-Wold, Brandon CNS Lymphoma: Clinical Pearls and Management Considerations |
title | CNS Lymphoma: Clinical Pearls and Management
Considerations |
title_full | CNS Lymphoma: Clinical Pearls and Management
Considerations |
title_fullStr | CNS Lymphoma: Clinical Pearls and Management
Considerations |
title_full_unstemmed | CNS Lymphoma: Clinical Pearls and Management
Considerations |
title_short | CNS Lymphoma: Clinical Pearls and Management
Considerations |
title_sort | cns lymphoma: clinical pearls and management
considerations |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275513/ https://www.ncbi.nlm.nih.gov/pubmed/35832688 |
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