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The Futility of Futility Analyses in Adjuvant Trials in Hormone Receptor–Positive Breast Cancer

An interim analysis is commonly used in phase III superiority trials to compare treatment arms, with the goal of terminating exposure of patients to ineffective or unsafe drugs or to identify highly effective therapies for earlier public disclosure. Traditionally, interim analyses have been designed...

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Detalles Bibliográficos
Autores principales: Lohmann, Ana Elisa, Ennis, Marguerite, Parulekar, Wendy R, Chen, Bingshu E, Tomlinson, George, Goodwin, Pamela J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275774/
https://www.ncbi.nlm.nih.gov/pubmed/35377437
http://dx.doi.org/10.1093/jnci/djac067