Development and Validation of a Dried Blood Spot Assay Using UHPLC-MS/MS to Identify and Quantify 12 Antihypertensive Drugs and 4 Active Metabolites: Clinical Needs and Analytical Limitations

As nonadherence to antihypertensive drugs (AHDs) can increase the risk of cardiovascular events, hospitalization, and higher costs, there is a need for a reliable, objective, and easy method to assess nonadherence in patients. The dried blood spot (DBS) sampling method used to measure drug concentra...

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Detalles Bibliográficos
Autores principales: Peeters, Laura E. J., Bahmany, Soma, Dekker, Tim, Aliawi, Aya, van Domburg, Bart, Versmissen, Jorie, Koch, Birgit C. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Therapeutic Drug Monitoring 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275854/
https://www.ncbi.nlm.nih.gov/pubmed/35383727
http://dx.doi.org/10.1097/FTD.0000000000000984

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275854/
https://www.ncbi.nlm.nih.gov/pubmed/35383727
http://dx.doi.org/10.1097/FTD.0000000000000984

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