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IFC-305 attenuates renal ischemia-reperfusion injury by promoting the production of hydrogen sulfide (H(2)S) via suppressing the promoter methylation of cystathionine γ-lyase (CSE)

Renal ischemia-reperfusion (I/R) injury is characterized by elevated expression of homocysteine and decreased production of hydrogen sulfide (H(2)S). Cystathionine γ-lyase (CSE) is a key factor in the onset of renal I/R injury, while IFC-305 can regulate the expression of CSE via epigenetic modifica...

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Detalles Bibliográficos
Autores principales: Jiang, Jie, Wen, Chuling, Li, Yi, Liu, Guohui, Chen, Zijun, Zheng, Dongwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275864/
https://www.ncbi.nlm.nih.gov/pubmed/35549822
http://dx.doi.org/10.1080/21655979.2022.2062105