Cargando…

Oxymatrine induces anti-tumor response in cervical cancer by modulating circ_0008460/miR-197-3p/ribonucleotide reductase subunit M2 (RRM2)

Oxymatrine (OMT) has exhibited an anti-cancer role in human cancers, including cervical cancer (CC). The dysregulated circular RNAs (circRNAs) are key regulators in cancer biology, and circ_0008460 was upregulated in CC. This study was performed to investigate the circRNA-based molecular mechanism f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Siwei, Zhang, Heng, Jiao, Yunping, Song, Xiao, Wei, Lei, Liu, Xing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275878/ https://www.ncbi.nlm.nih.gov/pubmed/35609310 http://dx.doi.org/10.1080/21655979.2022.2078943

Ejemplares similares

Sorafenib Inhibits Ribonucleotide Reductase Regulatory Subunit M2 (RRM2) in Hepatocellular Carcinoma Cells
por: Yang, Pei-Ming, et al.
Publicado: (2020)

The Clinical and Prognostic Significance of Ribonucleotide Reductase Subunits RRM1 and RRM2 mRNA Levels in Patients with Chronic Lymphocytic Leukemia
por: Chatzidavid, Sevastianos, et al.
Publicado: (2023)

Tumor suppressor FOXO3 regulates ribonucleotide reductase subunit RRM2B and impacts on survival of cancer patients
por: Cho, Er-Chieh, et al.
Publicado: (2014)

Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2)
por: Xia, Guanggai, et al.
Publicado: (2017)

Ribonucleotide reductase M2 (RRM2): Regulation, function and targeting strategy in human cancer
por: Zuo, Zanwen, et al.
Publicado: (2022)

Ribonucleotide reductase regulatory subunit M2 (RRM2) as a potential sero-diagnostic biomarker in non-small cell lung cancer
por: Zhou, Dandan, et al.
Publicado: (2023)

DHS (Trans-4,4’-Dihydroxystilbene) Suppresses DNA Replication and Tumor Growth by Inhibiting RRM2 (Ribonucleotide Reductase Regulatory Subunit M2)
por: Chen, Chi-Wei, et al.
Publicado: (2018)

Downregulation of ribonucleotide reductase subunits M2 induces apoptosis and G1 arrest of cervical cancer cells
por: Wang, Nan, et al.
Publicado: (2018)

Targeting the Large Subunit of Human Ribonucleotide Reductase for Cancer Chemotherapy
por: Wijerathna, Sanath R., et al.
Publicado: (2011)

Prognostic and Immunological Potential of Ribonucleotide Reductase Subunits in Liver Cancer
por: Yin, Xin, et al.
Publicado: (2023)

Ribonucleotide reductase subunit switching in hepatoblastoma drug response and relapse
por: Brown, Anthony, et al.
Publicado: (2023)

In vivo function of the murid herpesvirus-4 ribonucleotide reductase small subunit
por: Milho, Ricardo, et al.
Publicado: (2011)

Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication
por: Foskolou, Iosifina P., et al.
Publicado: (2017)

High Expression of Ribonucleotide Reductase Subunit M2 Correlates with Poor Prognosis of Hepatocellular Carcinoma
por: Lee, Boin, et al.
Publicado: (2014)

Ribonucleotide reductase small subunit M2 is a master driver of aggressive prostate cancer
por: Mazzu, Ying Z., et al.
Publicado: (2020)

Human equilibrative nucleoside transporter-1 (hENT1) and ribonucleotide reductase regulatory subunit M1 (RRM1) expression; do they have survival impact to pancreatic cancer?
por: Hwang, Dae Wook, et al.
Publicado: (2020)

Vaccinia Virus–Encoded Ribonucleotide Reductase Subunits Are Differentially Required for Replication and Pathogenesis
por: Gammon, Don B., et al.
Publicado: (2010)

Convergent allostery in ribonucleotide reductase
por: Thomas, William C., et al.
Publicado: (2019)

The periodic table of ribonucleotide reductases
por: Ruskoski, Terry B., et al.
Publicado: (2021)

Ribonucleotide Reductase Subunit M2 Can Be New Molecular Target and Prognostic Biomarker of Hepatocellular Carcinoma
por: Kim, Hee Yeon, et al.
Publicado: (2014)

Prognostic and therapeutic significance of ribonucleotide reductase small subunit M2 in estrogen-negative breast cancers
por: Zhang, Hang, et al.
Publicado: (2014)

A Novel Clade of Unique Eukaryotic Ribonucleotide Reductase R2 Subunits is Exclusive to Apicomplexan Parasites
por: Munro, James B., et al.
Publicado: (2013)

Ribonucleotide reductase subunit M2 as a novel target for clear-cell renal cell carcinoma
por: Zou, Yun, et al.
Publicado: (2019)

A pan-cancer analysis of the oncogenic role of ribonucleotide reductase subunit M2 in human tumors
por: Li, Yaqun, et al.
Publicado: (2022)

Regulatory Role of Ribonucleotide Reductase Subunit M2 in Hepatocyte Growth and Pathogenesis of Hepatitis C Virus
por: Kitab, Bouchra, et al.
Publicado: (2023)

Bacillus subtilis Class Ib Ribonucleotide Reductase: High Activity and Dynamic Subunit Interactions
por: Parker, Mackenzie J., et al.
Publicado: (2014)

Hug1 is an intrinsically disordered protein that inhibits ribonucleotide reductase activity by directly binding Rnr2 subunit
por: Meurisse, Julie, et al.
Publicado: (2014)

The tyrosyl free radical in ribonucleotide reductase.
por: Gräslund, A, et al.
Publicado: (1985)

Regulation of ribonucleotide reductase M2 expression by the upstream AUGs
por: Dong, Zizheng, et al.
Publicado: (2005)

Subunit and small-molecule interaction of ribonucleotide reductases via surface plasmon resonance biosensor analyses
por: Crona, Mikael, et al.
Publicado: (2010)

Novel ATP-cone-driven allosteric regulation of ribonucleotide reductase via the radical-generating subunit
por: Rozman Grinberg, Inna, et al.
Publicado: (2018)

Functional link between mitochondria and Rnr3, the minor catalytic subunit of yeast ribonucleotide reductase
por: Corcoles-Saez, Isaac, et al.
Publicado: (2019)

Differential accumulation of ribonucleotide reductase subunits in clam oocytes: the large subunit is stored as a polypeptide, the small subunit as untranslated mRNA
Publicado: (1986)

Ribonucleotide reductase small subunit M2 serves as a prognostic biomarker and predicts poor survival of colorectal cancers
por: Liu, Xiyong, et al.
Publicado: (2013)

Ribonucleotide reductase regulatory subunit M2 drives glioblastoma TMZ resistance through modulation of dNTP production
por: Perrault, Ella N., et al.
Publicado: (2023)

Comprehensive bioinformatics analysis of ribonucleoside diphosphate reductase subunit M2(RRM2) gene correlates with prognosis and tumor immunotherapy in pan-cancer
por: Wu, Liyuan, et al.
Publicado: (2022)

Rational polynomial representation of ribonucleotide reductase activity
por: Radivoyevitch, Tomas, et al.
Publicado: (2005)

Ribonucleotide reductases: essential enzymes for bacterial life
por: Torrents, Eduard
Publicado: (2014)

Knockdown of ribonucleotide reductase regulatory subunit M2 increases the drug sensitivity of chronic myeloid leukemia to imatinib-based therapy
por: Liu, Chunshui, et al.
Publicado: (2019)

CREB1 directly activates the transcription of ribonucleotide reductase small subunit M2 and promotes the aggressiveness of human colorectal cancer
por: Fang, Zejun, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_7jih4d4dmpq6dchksh4oqr9foa