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Recombinant human klotho protects against hydrogen peroxide-mediated injury in human retinal pigment epithelial cells via the PI3K/Akt-Nrf2/HO-1 signaling pathway

Globally, age-related macular degeneration (AMD) is a common irreversible ophthalmopathy. Oxidative stress of retinal pigment epithelial cells is involved in AMD occurrence and development. Klotho is an anti-aging protein with antioxidant properties. We investigated the protective properties of Klot...

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Detalles Bibliográficos
Autores principales:	Wen, Xuewei, Li, Song, Zhang, Yanfei, Zhu, Liang, Xi, Xiaoting, Zhang, Shuyuan, Li, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275962/ https://www.ncbi.nlm.nih.gov/pubmed/35543385 http://dx.doi.org/10.1080/21655979.2022.2071023

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