T staging with functional and radiomics parameters of computed tomography in colorectal cancer patients
Preoperative T staging is closely related to operation planning and prognosis of colorectal cancer (CRC). This study aimed to re-investigate the value of computed tomography (CT) in T stage evaluation of CRC patients with both functional and radiomics parameters. The functional and radiomics paramet...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276127/ https://www.ncbi.nlm.nih.gov/pubmed/35623068 http://dx.doi.org/10.1097/MD.0000000000029244 |
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author | Dou, Yafang Liu, Yingying Kong, Xiancheng Yang, Shangying |
author_facet | Dou, Yafang Liu, Yingying Kong, Xiancheng Yang, Shangying |
author_sort | Dou, Yafang |
collection | PubMed |
description | Preoperative T staging is closely related to operation planning and prognosis of colorectal cancer (CRC). This study aimed to re-investigate the value of computed tomography (CT) in T stage evaluation of CRC patients with both functional and radiomics parameters. The functional and radiomics parameters of CT images and the clinical information were collected from 32 CRC patients. The radiomics parameters were measured based on manually labelled 5-mm circles using software Syngo. The radiomics parameters were computed based on labelled tumor regions using Python software package. A total of 125 parameters were collected and analyzed by using decision tree analysis. The decision tree analysis identified 6 rules. Based on the rules, the shape elongation, flow extraction of nodule and blood volume of tumor region were found to be of significance and could define a high-risk group and a low-risk group. This study shows the combination of functional parameters and radiomics parameters of CT is helpful for the diagnosis and T staging of CRC. |
format | Online Article Text |
id | pubmed-9276127 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-92761272022-07-13 T staging with functional and radiomics parameters of computed tomography in colorectal cancer patients Dou, Yafang Liu, Yingying Kong, Xiancheng Yang, Shangying Medicine (Baltimore) 6800 Preoperative T staging is closely related to operation planning and prognosis of colorectal cancer (CRC). This study aimed to re-investigate the value of computed tomography (CT) in T stage evaluation of CRC patients with both functional and radiomics parameters. The functional and radiomics parameters of CT images and the clinical information were collected from 32 CRC patients. The radiomics parameters were measured based on manually labelled 5-mm circles using software Syngo. The radiomics parameters were computed based on labelled tumor regions using Python software package. A total of 125 parameters were collected and analyzed by using decision tree analysis. The decision tree analysis identified 6 rules. Based on the rules, the shape elongation, flow extraction of nodule and blood volume of tumor region were found to be of significance and could define a high-risk group and a low-risk group. This study shows the combination of functional parameters and radiomics parameters of CT is helpful for the diagnosis and T staging of CRC. Lippincott Williams & Wilkins 2022-05-27 /pmc/articles/PMC9276127/ /pubmed/35623068 http://dx.doi.org/10.1097/MD.0000000000029244 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) |
spellingShingle | 6800 Dou, Yafang Liu, Yingying Kong, Xiancheng Yang, Shangying T staging with functional and radiomics parameters of computed tomography in colorectal cancer patients |
title | T staging with functional and radiomics parameters of computed tomography in colorectal cancer patients |
title_full | T staging with functional and radiomics parameters of computed tomography in colorectal cancer patients |
title_fullStr | T staging with functional and radiomics parameters of computed tomography in colorectal cancer patients |
title_full_unstemmed | T staging with functional and radiomics parameters of computed tomography in colorectal cancer patients |
title_short | T staging with functional and radiomics parameters of computed tomography in colorectal cancer patients |
title_sort | t staging with functional and radiomics parameters of computed tomography in colorectal cancer patients |
topic | 6800 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276127/ https://www.ncbi.nlm.nih.gov/pubmed/35623068 http://dx.doi.org/10.1097/MD.0000000000029244 |
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