T staging with functional and radiomics parameters of computed tomography in colorectal cancer patients

Preoperative T staging is closely related to operation planning and prognosis of colorectal cancer (CRC). This study aimed to re-investigate the value of computed tomography (CT) in T stage evaluation of CRC patients with both functional and radiomics parameters. The functional and radiomics paramet...

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Autores principales: Dou, Yafang, Liu, Yingying, Kong, Xiancheng, Yang, Shangying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276127/
https://www.ncbi.nlm.nih.gov/pubmed/35623068
http://dx.doi.org/10.1097/MD.0000000000029244
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author Dou, Yafang
Liu, Yingying
Kong, Xiancheng
Yang, Shangying
author_facet Dou, Yafang
Liu, Yingying
Kong, Xiancheng
Yang, Shangying
author_sort Dou, Yafang
collection PubMed
description Preoperative T staging is closely related to operation planning and prognosis of colorectal cancer (CRC). This study aimed to re-investigate the value of computed tomography (CT) in T stage evaluation of CRC patients with both functional and radiomics parameters. The functional and radiomics parameters of CT images and the clinical information were collected from 32 CRC patients. The radiomics parameters were measured based on manually labelled 5-mm circles using software Syngo. The radiomics parameters were computed based on labelled tumor regions using Python software package. A total of 125 parameters were collected and analyzed by using decision tree analysis. The decision tree analysis identified 6 rules. Based on the rules, the shape elongation, flow extraction of nodule and blood volume of tumor region were found to be of significance and could define a high-risk group and a low-risk group. This study shows the combination of functional parameters and radiomics parameters of CT is helpful for the diagnosis and T staging of CRC.
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spelling pubmed-92761272022-07-13 T staging with functional and radiomics parameters of computed tomography in colorectal cancer patients Dou, Yafang Liu, Yingying Kong, Xiancheng Yang, Shangying Medicine (Baltimore) 6800 Preoperative T staging is closely related to operation planning and prognosis of colorectal cancer (CRC). This study aimed to re-investigate the value of computed tomography (CT) in T stage evaluation of CRC patients with both functional and radiomics parameters. The functional and radiomics parameters of CT images and the clinical information were collected from 32 CRC patients. The radiomics parameters were measured based on manually labelled 5-mm circles using software Syngo. The radiomics parameters were computed based on labelled tumor regions using Python software package. A total of 125 parameters were collected and analyzed by using decision tree analysis. The decision tree analysis identified 6 rules. Based on the rules, the shape elongation, flow extraction of nodule and blood volume of tumor region were found to be of significance and could define a high-risk group and a low-risk group. This study shows the combination of functional parameters and radiomics parameters of CT is helpful for the diagnosis and T staging of CRC. Lippincott Williams & Wilkins 2022-05-27 /pmc/articles/PMC9276127/ /pubmed/35623068 http://dx.doi.org/10.1097/MD.0000000000029244 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/)
spellingShingle 6800
Dou, Yafang
Liu, Yingying
Kong, Xiancheng
Yang, Shangying
T staging with functional and radiomics parameters of computed tomography in colorectal cancer patients
title T staging with functional and radiomics parameters of computed tomography in colorectal cancer patients
title_full T staging with functional and radiomics parameters of computed tomography in colorectal cancer patients
title_fullStr T staging with functional and radiomics parameters of computed tomography in colorectal cancer patients
title_full_unstemmed T staging with functional and radiomics parameters of computed tomography in colorectal cancer patients
title_short T staging with functional and radiomics parameters of computed tomography in colorectal cancer patients
title_sort t staging with functional and radiomics parameters of computed tomography in colorectal cancer patients
topic 6800
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276127/
https://www.ncbi.nlm.nih.gov/pubmed/35623068
http://dx.doi.org/10.1097/MD.0000000000029244
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