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Mantle cell lymphoma presenting with severe upper gastrointestinal bleeding: A case report
INTRODUCTION: Although it usually involves extranodal sites such as the gastrointestinal tract in more than 80% of cases, mantle cell lymphoma is considered a rare cause of gastrointestinal bleeding, especially severe and life-threatening bleeding. PATIENT CONCERN: A 60-year-old man with peptic ulce...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276165/ https://www.ncbi.nlm.nih.gov/pubmed/35687772 http://dx.doi.org/10.1097/MD.0000000000029236 |
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author | Ali, Khaled Habib, Mhd Baraa Alloush, Ferial Yassin, Mohamed A. |
author_facet | Ali, Khaled Habib, Mhd Baraa Alloush, Ferial Yassin, Mohamed A. |
author_sort | Ali, Khaled |
collection | PubMed |
description | INTRODUCTION: Although it usually involves extranodal sites such as the gastrointestinal tract in more than 80% of cases, mantle cell lymphoma is considered a rare cause of gastrointestinal bleeding, especially severe and life-threatening bleeding. PATIENT CONCERN: A 60-year-old man with peptic ulcer disease, who presented with severe upper gastrointestinal (GI) bleeding and large gastric ulcer. DIAGNOSIS: Primary gastric mantle cell lymphoma. INTERVENTIONS: He was treated conservatively with blood transfusion and started on Traneximic acid for 3 days. Then, the patient underwent urgent hemostatic radiotherapy. OUTCOMES: The patient became stable and kept in the hospital for monitoring with a definite diagnosis of stage IV Mantle cell lymphoma is made. CONCLUSION: Mantle cell lymphoma should be kept in mind when assessing massive upper GI bleeding, as an unusual cause of bleeding gastric ulcer, given that bleeding is an uncommon presenting feature of GI lymphoma. |
format | Online Article Text |
id | pubmed-9276165 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-92761652022-07-13 Mantle cell lymphoma presenting with severe upper gastrointestinal bleeding: A case report Ali, Khaled Habib, Mhd Baraa Alloush, Ferial Yassin, Mohamed A. Medicine (Baltimore) 5700 INTRODUCTION: Although it usually involves extranodal sites such as the gastrointestinal tract in more than 80% of cases, mantle cell lymphoma is considered a rare cause of gastrointestinal bleeding, especially severe and life-threatening bleeding. PATIENT CONCERN: A 60-year-old man with peptic ulcer disease, who presented with severe upper gastrointestinal (GI) bleeding and large gastric ulcer. DIAGNOSIS: Primary gastric mantle cell lymphoma. INTERVENTIONS: He was treated conservatively with blood transfusion and started on Traneximic acid for 3 days. Then, the patient underwent urgent hemostatic radiotherapy. OUTCOMES: The patient became stable and kept in the hospital for monitoring with a definite diagnosis of stage IV Mantle cell lymphoma is made. CONCLUSION: Mantle cell lymphoma should be kept in mind when assessing massive upper GI bleeding, as an unusual cause of bleeding gastric ulcer, given that bleeding is an uncommon presenting feature of GI lymphoma. Lippincott Williams & Wilkins 2022-06-10 /pmc/articles/PMC9276165/ /pubmed/35687772 http://dx.doi.org/10.1097/MD.0000000000029236 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) |
spellingShingle | 5700 Ali, Khaled Habib, Mhd Baraa Alloush, Ferial Yassin, Mohamed A. Mantle cell lymphoma presenting with severe upper gastrointestinal bleeding: A case report |
title | Mantle cell lymphoma presenting with severe upper gastrointestinal bleeding: A case report |
title_full | Mantle cell lymphoma presenting with severe upper gastrointestinal bleeding: A case report |
title_fullStr | Mantle cell lymphoma presenting with severe upper gastrointestinal bleeding: A case report |
title_full_unstemmed | Mantle cell lymphoma presenting with severe upper gastrointestinal bleeding: A case report |
title_short | Mantle cell lymphoma presenting with severe upper gastrointestinal bleeding: A case report |
title_sort | mantle cell lymphoma presenting with severe upper gastrointestinal bleeding: a case report |
topic | 5700 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276165/ https://www.ncbi.nlm.nih.gov/pubmed/35687772 http://dx.doi.org/10.1097/MD.0000000000029236 |
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