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Overexpression of c-Myc-dependent heterogeneous nuclear ribonucleoprotein A1 promotes proliferation and inhibits apoptosis in NOTCH1-mutated chronic lymphocytic leukemia cells

BACKGROUND: NOTCH1 mutation is an essential molecular biologic aberration in chronic lymphocytic leukemia (CLL). CLL patients with NOTCH1 mutation have shown an unfavorable survival and a poor response to chemoimmunotherapy. This study aims to present the mechanisms of adverse prognosis caused by NO...

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Detalles Bibliográficos
Autores principales:	Zou, Yixin, Tang, Hanning, Miao, Yi, Zhu, Huayuan, Wang, Li, Fan, Lei, Fu, Jianxin, Xu, Wei, Li, Jianyong, Xia, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276458/ https://www.ncbi.nlm.nih.gov/pubmed/35730371 http://dx.doi.org/10.1097/CM9.0000000000002037

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