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Clonal structure, stability and dynamics of human memory B cells and circulating plasmablasts

Memory B cells persist for a lifetime and rapidly differentiate into antibody-producing plasmablasts and plasma cells upon antigen re-encounter. The clonal relationship and evolution of memory B cells and circulating plasmablasts is not well understood. Using single-cell sequencing combined with iso...

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Detalles Bibliográficos
Autores principales: Phad, Ganesh E., Pinto, Dora, Foglierini, Mathilde, Akhmedov, Murodzhon, Rossi, Riccardo L., Malvicini, Emilia, Cassotta, Antonino, Fregni, Chiara Silacci, Bruno, Ludovica, Sallusto, Federica, Lanzavecchia, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276532/
https://www.ncbi.nlm.nih.gov/pubmed/35761085
http://dx.doi.org/10.1038/s41590-022-01230-1

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