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Clonal structure, stability and dynamics of human memory B cells and circulating plasmablasts
Memory B cells persist for a lifetime and rapidly differentiate into antibody-producing plasmablasts and plasma cells upon antigen re-encounter. The clonal relationship and evolution of memory B cells and circulating plasmablasts is not well understood. Using single-cell sequencing combined with iso...
Autores principales: | Phad, Ganesh E., Pinto, Dora, Foglierini, Mathilde, Akhmedov, Murodzhon, Rossi, Riccardo L., Malvicini, Emilia, Cassotta, Antonino, Fregni, Chiara Silacci, Bruno, Ludovica, Sallusto, Federica, Lanzavecchia, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276532/ https://www.ncbi.nlm.nih.gov/pubmed/35761085 http://dx.doi.org/10.1038/s41590-022-01230-1 |
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