Cargando…
Admissions to a large tertiary care hospital and Omicron BA.1 and BA.2 SARS-CoV-2 polymerase chain reaction positivity: primary, contributing, or incidental COVID-19
OBJECTIVES: SARS-CoV-2 Omicron variants BA.1 and BA.2 seem to show reduced clinical severity compared with earlier variants. Therefore, we aimed to assess and classify the cause of hospitalization for patients with COVID-19 identified with these Omicron variants in our hospital. METHODS: A retrospec...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276536/ https://www.ncbi.nlm.nih.gov/pubmed/35842214 http://dx.doi.org/10.1016/j.ijid.2022.07.030 |
_version_ | 1784745752148312064 |
---|---|
author | Voor in ’t holt, Anne F. Haanappel, Cynthia P. Rahamat–Langendoen, Janette Molenkamp, Richard van Nood, Els van den Toorn, Leon M. Peeters, Robin P. van Rossum, Annemarie M.C. Severin, Juliëtte A. |
author_facet | Voor in ’t holt, Anne F. Haanappel, Cynthia P. Rahamat–Langendoen, Janette Molenkamp, Richard van Nood, Els van den Toorn, Leon M. Peeters, Robin P. van Rossum, Annemarie M.C. Severin, Juliëtte A. |
author_sort | Voor in ’t holt, Anne F. |
collection | PubMed |
description | OBJECTIVES: SARS-CoV-2 Omicron variants BA.1 and BA.2 seem to show reduced clinical severity compared with earlier variants. Therefore, we aimed to assess and classify the cause of hospitalization for patients with COVID-19 identified with these Omicron variants in our hospital. METHODS: A retrospective analysis was performed on all patients identified with the SARS-CoV-2 Omicron variant between December 23, 2021, and February 27, 2022. Patients with a positive SARS-CoV-2 polymerase chain reaction (PCR) upon clinical admission or during clinical admission were classified into four categories: (1) primary COVID-19, (2) admission-contributing COVID-19, (3) incidental COVID-19, and (4) undetermined COVID-19. RESULTS: We classified 172 COVID-19 Omicron patient admissions, including 151 adult and 21 pediatric patients. Of the adult patients, 45% were primary COVID-19 cases, 21% were admission-contributing, 31% were incidental, and 3% were undetermined. Of the pediatric patients, 19% were primary COVID-19 cases, 29% were admission-contributing, 38% were incidental, and 14% were undetermined. CONCLUSION: In the evolving landscape of COVID-19, the number of hospitalized patients with COVID-19 should be interpreted with caution. The different patient categories should be considered in public health policy decision-making and when informing the general public. |
format | Online Article Text |
id | pubmed-9276536 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. |
record_format | MEDLINE/PubMed |
spelling | pubmed-92765362022-07-14 Admissions to a large tertiary care hospital and Omicron BA.1 and BA.2 SARS-CoV-2 polymerase chain reaction positivity: primary, contributing, or incidental COVID-19 Voor in ’t holt, Anne F. Haanappel, Cynthia P. Rahamat–Langendoen, Janette Molenkamp, Richard van Nood, Els van den Toorn, Leon M. Peeters, Robin P. van Rossum, Annemarie M.C. Severin, Juliëtte A. Int J Infect Dis Short Communication OBJECTIVES: SARS-CoV-2 Omicron variants BA.1 and BA.2 seem to show reduced clinical severity compared with earlier variants. Therefore, we aimed to assess and classify the cause of hospitalization for patients with COVID-19 identified with these Omicron variants in our hospital. METHODS: A retrospective analysis was performed on all patients identified with the SARS-CoV-2 Omicron variant between December 23, 2021, and February 27, 2022. Patients with a positive SARS-CoV-2 polymerase chain reaction (PCR) upon clinical admission or during clinical admission were classified into four categories: (1) primary COVID-19, (2) admission-contributing COVID-19, (3) incidental COVID-19, and (4) undetermined COVID-19. RESULTS: We classified 172 COVID-19 Omicron patient admissions, including 151 adult and 21 pediatric patients. Of the adult patients, 45% were primary COVID-19 cases, 21% were admission-contributing, 31% were incidental, and 3% were undetermined. Of the pediatric patients, 19% were primary COVID-19 cases, 29% were admission-contributing, 38% were incidental, and 14% were undetermined. CONCLUSION: In the evolving landscape of COVID-19, the number of hospitalized patients with COVID-19 should be interpreted with caution. The different patient categories should be considered in public health policy decision-making and when informing the general public. The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2022-09 2022-07-13 /pmc/articles/PMC9276536/ /pubmed/35842214 http://dx.doi.org/10.1016/j.ijid.2022.07.030 Text en © 2022 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Short Communication Voor in ’t holt, Anne F. Haanappel, Cynthia P. Rahamat–Langendoen, Janette Molenkamp, Richard van Nood, Els van den Toorn, Leon M. Peeters, Robin P. van Rossum, Annemarie M.C. Severin, Juliëtte A. Admissions to a large tertiary care hospital and Omicron BA.1 and BA.2 SARS-CoV-2 polymerase chain reaction positivity: primary, contributing, or incidental COVID-19 |
title | Admissions to a large tertiary care hospital and Omicron BA.1 and BA.2 SARS-CoV-2 polymerase chain reaction positivity: primary, contributing, or incidental COVID-19 |
title_full | Admissions to a large tertiary care hospital and Omicron BA.1 and BA.2 SARS-CoV-2 polymerase chain reaction positivity: primary, contributing, or incidental COVID-19 |
title_fullStr | Admissions to a large tertiary care hospital and Omicron BA.1 and BA.2 SARS-CoV-2 polymerase chain reaction positivity: primary, contributing, or incidental COVID-19 |
title_full_unstemmed | Admissions to a large tertiary care hospital and Omicron BA.1 and BA.2 SARS-CoV-2 polymerase chain reaction positivity: primary, contributing, or incidental COVID-19 |
title_short | Admissions to a large tertiary care hospital and Omicron BA.1 and BA.2 SARS-CoV-2 polymerase chain reaction positivity: primary, contributing, or incidental COVID-19 |
title_sort | admissions to a large tertiary care hospital and omicron ba.1 and ba.2 sars-cov-2 polymerase chain reaction positivity: primary, contributing, or incidental covid-19 |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276536/ https://www.ncbi.nlm.nih.gov/pubmed/35842214 http://dx.doi.org/10.1016/j.ijid.2022.07.030 |
work_keys_str_mv | AT voorintholtannef admissionstoalargetertiarycarehospitalandomicronba1andba2sarscov2polymerasechainreactionpositivityprimarycontributingorincidentalcovid19 AT haanappelcynthiap admissionstoalargetertiarycarehospitalandomicronba1andba2sarscov2polymerasechainreactionpositivityprimarycontributingorincidentalcovid19 AT rahamatlangendoenjanette admissionstoalargetertiarycarehospitalandomicronba1andba2sarscov2polymerasechainreactionpositivityprimarycontributingorincidentalcovid19 AT molenkamprichard admissionstoalargetertiarycarehospitalandomicronba1andba2sarscov2polymerasechainreactionpositivityprimarycontributingorincidentalcovid19 AT vannoodels admissionstoalargetertiarycarehospitalandomicronba1andba2sarscov2polymerasechainreactionpositivityprimarycontributingorincidentalcovid19 AT vandentoornleonm admissionstoalargetertiarycarehospitalandomicronba1andba2sarscov2polymerasechainreactionpositivityprimarycontributingorincidentalcovid19 AT peetersrobinp admissionstoalargetertiarycarehospitalandomicronba1andba2sarscov2polymerasechainreactionpositivityprimarycontributingorincidentalcovid19 AT vanrossumannemariemc admissionstoalargetertiarycarehospitalandomicronba1andba2sarscov2polymerasechainreactionpositivityprimarycontributingorincidentalcovid19 AT severinjuliettea admissionstoalargetertiarycarehospitalandomicronba1andba2sarscov2polymerasechainreactionpositivityprimarycontributingorincidentalcovid19 |