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Surface cholesterol-enriched domains specifically promote invasion of breast cancer cell lines by controlling invadopodia and extracellular matrix degradation

Tumor cells exhibit altered cholesterol content. However, cholesterol structural subcellular distribution and implication in cancer cell invasion are poorly understood mainly due to difficulties to investigate cholesterol both quantitatively and qualitatively and to compare isogenic cell models. Her...

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Detalles Bibliográficos
Autores principales: Maja, Mauriane, Mohammed, Danahe, Dumitru, Andra C., Verstraeten, Sandrine, Lingurski, Maxime, Mingeot-Leclercq, Marie-Paule, Alsteens, David, Tyteca, Donatienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276565/
https://www.ncbi.nlm.nih.gov/pubmed/35819726
http://dx.doi.org/10.1007/s00018-022-04426-8