A stable cyclized antimicrobial peptide derived from LL-37 with host immunomodulatory effects and activity against uropathogens

The increasing antibiotic resistance among uropathogenic bacteria warrants alternative therapeutic strategies. We demonstrate the potential of the synthetic peptide CD4-PP, designed by dimerization and backbone cyclization of the shortest antimicrobial region of human cathelicidin, LL-37. CD4-PP is...

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Detalles Bibliográficos
Autores principales: White, John Kerr, Muhammad, Taj, Alsheim, Emelie, Mohanty, Soumitra, Blasi-Romero, Anna, Gunasekera, Sunithi, Strömstedt, Adam A., Ferraz, Natalia, Göransson, Ulf, Brauner, Annelie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276586/
https://www.ncbi.nlm.nih.gov/pubmed/35821354
http://dx.doi.org/10.1007/s00018-022-04440-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276586/
https://www.ncbi.nlm.nih.gov/pubmed/35821354
http://dx.doi.org/10.1007/s00018-022-04440-w

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